International Research Review

International Research Review2021-03-08T11:41:45-05:00

The two new SARS-CoV-2 variants scientists are tracking

by Mariana Bego The World Health Organization (WHO) has recently introduced a new Variant of Interest (VOI) titled Mu or B.1.621. This new variant is becoming increasingly prevalent in parts of South America, namely Colombia and Ecuador. South African scientists are also closely monitoring the development of another new variant in the region called C.1.2, which has not yet been classified as a VOI. [...]

September 14, 2021|International research review|

Review of host factors highjacked by SARS-CoV-2

By Mariana Bego A recent state-of-the-art review in Nature Microbiology summarizes the latest evidence regarding the molecules in our cells that allow SARS-CoV-2 to infect us and how these may give us clues to discover new anti-viral drugs. As intracellular parasites, viruses depend on host cell factors and machinery to grow and replicate. This review summarizes the host factors needed for SARS-CoV-2 replication cycles. [...]

September 14, 2021|International research review|

Concerns about legal challenges to COVID-19 public health orders

By Alexis Palmer-Fluevog The field of public health has never been without critics. Globally, public health officers wield varying amounts of power, with the North American court systems historically respecting and upholding public health order. In this article published in the New England Journal of Medicine, Mello and colleagues voice their concerns about the increasing number of legal challenges in the US to COVID-19 [...]

September 14, 2021|International research review|

Outcomes of COVID-19 in children and adolescents with cancer

By Marija Djekic-Ivankovic Previous studies have shown that children with COVID-19 generally have a milder disease course compared to adults. However, children with cancer have a higher risk of severe disease due to infection with other respiratory viruses, suggesting they may also be at higher risk for COVID-19 complications. A recent multi-national study, published in Lancet Oncology, indicated that 20% of children and adolescents [...]

September 7, 2021|International research review|

Delta doubles risk of hospitalization compared to Alpha, study finds

New research out of England published in The Lancet Infectious Diseases suggests that hospitalization and visits to the emergency department are twice as likely with the variant of concern (VOC) Delta compared to the Alpha variant. These findings come at a time when Delta is surging worldwide, forewarning its significant strain on healthcare systems. The study included more than 8,000 individuals infected with the [...]

September 7, 2021|International research review|

Administering a third booster shot: an ethical dilemma

By Varun C. Anipindi While countries around the world are working to get their populations vaccinated, the emergence of SARS-CoV-2 variants of concern (VOCs) has threatened our return to normalcy. With the rise of breakthrough infections associated with the Delta variant, public health agencies in middle- and high-income countries are debating the need for booster shots to ensure enhanced protection against COVID-19. However, this [...]

August 31, 2021|International research review|

A snapshot of the current landscape of COVID-19 vaccines

By Varun C. Anipindi As the world – and Canada – deals with increasing case numbers due to variants, scientists from the Imperial College London provide a snapshot of emerging data on real-life efficacy of COVID-19 vaccines against variants. In this Nature Reviews Immunology article, they also discuss future considerations needed to overcome this pandemic.   While several vaccines have been authorized for use [...]

August 24, 2021|International research review|

Another tool to combat COVID-19: the Moderna vaccine is shown to be safe and efficacious among adolescents 12-17 years of age

By Alexis Palmer-Fluevog In their recent publication in The New England Journal of Medicine, researchers Dr. Kashir Ali, Dr. Gary Berman and colleagues presented the interim results of the Moderna vaccine trial in adolescents aged 12 to 17. The authors highlighted the safety of the vaccine and the 93% efficacy shown in this phase 2-3 trial. If granted approval, this vaccine will be the [...]

August 24, 2021|International research review|

Back-to-university checklist: books, pens, vaccine

By Alexis Palmer-Fluevog Researchers from Ontario indicate that about 80% of students enrolled at a large Canadian university between June and October 2020, prior to the availability of vaccines, intended to receive a COVID-19 vaccine once it was offered. In their recent publication in PLOS One, the researchers highlight personal perspectives around COVID-19 vaccines and explore the willingness of students to receive a vaccine. [...]

August 17, 2021|International research review|
Go to Top