International Research Review

International Research Review2021-03-08T11:41:45-05:00

Vaccinating Children against COVID-19: the Benefits Outweigh the Risks

As a safe and effective COVID-19 vaccine is now available for school-aged children, it is important to reflect on the multiple streams of benefits arising from their rapid roll-out. Successful immunization campaigns protect children from severe disease, help lower community transmission of the virus, allow the re-establishment of social networks, see the continuance of in-class schooling, and permit the full resumption of extra-curricular activities.

December 1, 2021|International research review|

How do we combat vaccine hesitancy? Let’s talk about vaccine effectiveness!

In this Canadian study published in JAMA, researchers wanted to know if the type of information provided about a vaccine could affect people’s likelihood of accepting it. Findings indicate that providing information on how well vaccines prevent death, rather than how well they prevent symptomatic disease, made participants more likely to accept the vaccine. The research team carried out an online survey with a [...]

October 12, 2021|International research review|

How common is long COVID in the UK? The answer depends on how you measure it

By Marija Djekic-Ivankovic Long COVID is an emerging phenomenon that is not yet fully understood or well defined. This technical article, recently released by UK Office for National Statistics, presents a range of prevalence estimates regarding the number of people who experience symptoms beyond the acute phase of COVID-19 infection, commonly referred to as "long COVID". Researchers indicate that long COVID may affect 3% [...]

October 5, 2021|International research review|

Will the pandemic go on indefinitely?

By Mercedes Yanes Lane No, pandemics do not last forever. In this article published in Immunity, the authors provide a description of the epidemiological and immunological measures that underlie the transition from a pandemic state to an endemic state. Measures such as immune efficacy, disease prevalence, severity of disease, and age distribution all play a role in a disease becoming endemic. A disease is [...]

October 5, 2021|International research review|

To boost or not to boost? Considerations towards administering an additional COVID-19 dose

By Mariana Bego Rising COVID-19 cases spurred by the highly transmissible Delta variant have led policymakers and researchers to consider the need for vaccine booster doses. The goals: reduce the number of COVID-19 cases and enhance immunity in vaccinated people. Although tempting, these decisions should be evidence-based and consider the benefits and risks for individuals and society as a whole. Recent publications and recommendations [...]

September 28, 2021|International research review|

Vaccines for children coming soon, but how do we keep schools safe?

By Mercedes Yanes Lane On September 20th, 2021, Pfizer-BioNtech announced preliminary results from its phase 2/3 trial in children ages 5 to 11 with a two-dose vaccine scheme.1 With this information, regulatory agencies can now assess the safety and efficacy of the vaccine on their end with the aim of approving the lower dose of this vaccine in children. However, non-vaccine strategies need to [...]

September 28, 2021|International research review|

COVID-19 vaccine effectiveness against hospitalization and emergency department visits: a comparison

By Mariana Bego COVID-19 vaccines are effective at preventing hospitalizations and emergency department visits caused by the Delta variant, according to several recent publications. The data also indicate that Moderna’s vaccine is significantly more effective against Delta than Pfizer-BioNTech or Johnson & Johnson’s Janssen. Real-world data show that vaccines remain highly effective at reducing COVID-19 related hospitalizations and emergency department (ED) visits, even in [...]

September 21, 2021|International research review|

Humoral immunity to seasonal coronaviruses may be associated with better outcomes in COVID-19

By Varun C. Anipindi People infected with SARS-CoV-2 can experience a wide range of outcomes, ranging from asymptomatic infection to severe disease and death. While emerging evidence indicates that antibodies may represent a major correlate of protection, the specific mechanisms by which they influence overall disease outcomes is unknown.  In this pre-print, not yet peer-reviewed, Kaplonek et al. conducted an in-depth profiling of the [...]

September 21, 2021|International research review|

Increase in SARS-CoV-2 Seroprevalence in the U.S. from July 2020 to May 2021

By Marija Djekic-Ivankovic The proportion of people in the U.S. with SARS-CoV-2 antibodies remains uncertain. A new study published in JAMA used a sample of 1.44 million blood samples from July 2020 through May 2021 to estimate the SARS-CoV-2 seroprevalence in the general US population aged 16 years and older. Findings indicate that the estimated SARS-CoV-2 seroprevalence increased over time and varied by age, [...]

September 14, 2021|International research review|
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