Published Research Papers

Published Research Papers2022-05-20T15:21:43-04:00

Publications from CITF-funded Research

McClymont E, Albert AY, Alton GD, Boucoiran I, Castillo E, Fell DB, Kuret V, Poliquin V, Reeve T, Scott H, Sprague AE, Carson G, Cassell K, Crane J, Elwood C, Joynt C, Murphy P, Murphy-Kaulbeck L, Saunders S, Shah P, Snelgrove JW, van Schalkwyk J, Yudin MH, Money D; CANCOVID-Preg Team. Association of SARS-CoV-2 Infection During Pregnancy With Maternal and Perinatal Outcomes. JAMA. 2022 May 2. doi: 10.1001/jama.2022.5906.

Reicherz F, Xu RY, Abu-Raya B, Majdoubi A, Michalski C, Golding L, Stojic A, Vineta M, Granoski M, Cieslak Z, Chacko A, Desai N, Sekirov I, Marchant DJ, Lavoie PM. Waning immunity against respiratory syncytial virus during the COVID-19 pandemic. Journal of Infectious Diseases. May 7, 2022. doi: org/10.1093/infdis/jiac192.

Mwimanzi, F., H. R. Lapointe, P. K. Cheung, Y. Sang, F. Yaseen, G. Umviligihozo, R. Kalikawe, S. Datwani, F. H. Omondi, L. Burns, L. Young, V. Leung, O. Agafitei, S. Ennis, W. Dong, S. Basra, L. Y. Lim, K. Ng, R. Pantophlet, C. J. Brumme, J. S. G. Montaner, N. Prystajecky, C. F. Lowe, M. L. DeMarco, D. T. Holmes, J. Simons, M. Niikura, M. G. Romney, Z. L. Brumme and M. A. Brockman (2022). Older adults mount less durable humoral responses to two doses of COVID-19 mRNA vaccine, but strong initial responses to a third dose. J Infect Dis; jiac199. doi: 10.1093/infdis/jiac199.

Racine É, Boivin G, Longtin Y, Mccormack D, Decaluwe H, Savard P, Cheng MP, Hamelin ME, Carbonneau J, Tadount F, Adams K, Bourdin B, Nantel S, Gilca V, Corbeil J, De Serres G, Quach-Thanh C. The REinfection in COVID‐19 Estimation of Risk (RECOVER) study: Reinfection and serology dynamics in a cohort of Canadian healthcare workers. Influenza Other Respir Viruses; 2022; 1-10. doi: 10.1111/irv.12997.

Widdifield J, Kwong JC, Chen S, Eder L, Benchimol EI, Kaplan GG, Hitchon C, Aviña-Zubieta JA, Lacaille D, Chung H, Bernatsky S. Vaccine effectiveness against SARS-CoV-2 infection and severe outcomes among individuals with immune-mediated inflammatory diseases tested between March 1 and Nov 22, 2021, in Ontario, Canada: a population-based analysis. The Lancet Rheumatology. 2022 Apr 14. doi: 10.1016/S2665-9913(22)00096-0 

Watts AW, Hutchison SM, Bettinger JA, Gadermann A, Oberle E, Oberlander TF, Goldfarb DM, Lavoie PM, Masse LC. COVID-19 Vaccine Intentions and Perceptions Among Public School Staff of the Greater Vancouver Metropolitan Area, British Columbia, Canada. Front. Public Health, 27 April 2022. doi: https://doi.org/10.3389/fpubh.2022.832444

Reedman CN, Drews SJ, Yi QL, Pambrun C, O’Brien SF. Changing Patterns of SARS-CoV-2 Seroprevalence among Canadian Blood Donors during the Vaccine Era. Microbiology Spectrum. 2022 Apr 12. doi: 10.1128/spectrum.00339-22

Bhatt M, Plint AC, Tang K, Malley R, Huy AP, McGahern C, Dawson J, Pelchat M, Dawson L, Varshney T, Arnold C, Galipeau Y, Austin M, Thampi N, Alnaji F, Langlois MA, Zemek RL. Household transmission of SARS-CoV-2 from unvaccinated asymptomatic and symptomatic household members with confirmed SARS-CoV-2 infection: an antibody-surveillance study. CMAJ Open. Apr 2022, 10 (2) E357-E366; doi: https://doi.org/10.9778/cmajo.20220026.

Nasreen S, Febriani Y, Velásquez García HA, Zhang G, Tadrous M, Buchan SA, Righolt CH, Mahmoud SM, Janjua NZ, Krajden M, De Serres G, Kwong JC. Effectiveness of COVID-19 vaccines against hospitalization and death in Canada: A multiprovincial test-negative design study. medRxiv.  2022.04.13.22273825; doi: https://doi.org/10.1101/2022.04.13.22273825

McMillan B, Marquez AC, Gaultier GN, Bartlett SR, Skowronski D, Levings M, Steiner T, Zlosnik J, Krajden M, Morshed M, Sekirov I, Jassem AN, Sadarangani M. Prospective Evaluation of Immunity After COVID-19 Vaccines: The PREVENT-COVID Study.

Banerjee A, Lew J, Kroeker A, Baid K, Aftanas P, Nirmalarajah K, Maguire F, Kozak R, McDonald R, Lang A, Gerdts V, Straus SE, Gilbert L, Li AX, Mozafarihasjin M, Walmsley S, Gingras AC, Wrana JL, Mazzulli T, Colwill K, McGeer AJ, Mubareka S, Falzarano D. Immunogenicity of convalescent and vaccinated sera against clinical isolates of ancestral SARS-CoV-2, beta, delta, and omicron variants. Med. 2022 Apr 13. doi:  10.1016/j.medj.2022.04.002

Nantel S, Bourdin B, Adams K, Carbonneau J, Rabezanaha H, Hamelin ME, McCormack D, Savard P, Longtin Y, Cheng M, DeSerres G, Corbeil J, Gilca V, Baz M, Boivin G, Quach C, Decaluwe H. Immunogenicity of Pfizer-BioNTech COVID-19 mRNA Primary Vaccination Series in Recovered Individuals Depends on Symptoms at Initial Infection. medRxiv. 2022 Jan 1. Doi: 10.1101/2022.03.29.22272714.

Hutchison SM, Watts A, Gadermann A, Oberle E, Oberlander TF, Lavoie PM, Mâsse LC. School staff and teachers during the second year of COVID-19: Higher anxiety symptoms, higher psychological distress, and poorer mental health compared to the general population. Journal of Affective Disorders Reports. 2022 Mar 17. doi: 10.1016/j.jadr.2022.100335.

Anand SS, Arnold C, Bangdiwala S, Bolotin S, Bowdish D, Chanchlani R, de Souza R, Desai D, Kandasamy S, Khan F, Khan Z, Langlois M-A, Limbachia J, Lear S, Loeb M, Loh L, Manoharan B, Nakka K, Pelchat M,  Punthakee Z, Schulze K, Williams N, Wahi G. What factors converged to create a COVID-19 hot-spot? Lessons from the South Asian community in Ontario. medRxiv. 2022 Apr 1. Doi: 10.1101/2022.04.01.22273252.

Goldfarb DM, Mâsse LC, Watts AW, Hutchison SM, Muttucomaroe L, Bosman ES, Barakauskas VE, Choi A, Dhillon N, Irvine MA, Reicherz F, O’Reilly C, Sediqi S, Xu RY, Razzaghian HR, Sadarangani M, Coombs D, O’Brien SF, Lavoie PM. SARS-CoV-2 seroprevalence among Vancouver public school staff in British Columbia, Canada: a cross-sectional study. BMJ Open. 2022 Apr 5. doi: 10.1136/bmjopen-2021-057846.

Jantzen R, Maltais M, Broet P. Socio-Demographic Factors Associated With COVID-19 Vaccine Hesitancy Among Middle-Aged Adults During the Quebec’s Vaccination Campaign. Front. Public Health, 18 March 2022 doi: https://doi.org/10.3389/fpubh.2022.756037

Deshayne B. Fell, Tavleen Dhinsa, Gillian D. Alton, Eszter Török, Sheryll Dimanlig-Cruz, Annette K. Regan, Ann E. Sprague, Sarah A. Buchan, Jeffrey C. Kwong, Sarah E. Wilson, Siri E. Håberg, Christopher A. Gravel, Kumanan Wilson, Darine El-Chaâr, Mark C. Walker, Jon Barrett, Shannon E. MacDonald, Nannette Okun, Prakesh S. Shah, Shelley D. Dougan, Sandra Dunn, Lise Bisnaire Association of COVID-19 Vaccination in Pregnancy With Adverse Peripartum Outcomes. JAMA. Published online March 24, 2022. doi: 10.1001/jama.2022.4255.

Lapointe HR, Mwimanzi F, Cheung PK, Sang Y, Yaseen F, Umviligihozo G, Kalikawe R, Speckmaier S, Moran-Garcia N, Datwani S, Duncan MC, Agafitei O, Ennis S, Young L, Ali H, Ganase B, Omondi FH, Dong W, Toy J, Sereda P, Burns L, Costiniuk CT, Cooper C, Anis A, Leung V, Holmes DT, DeMarco ML, Simons J, Hedgcock M, Prystajecky N, Lowe CF, Pantophlet R, Romney MG, Barrios R, Guillemi S, Brumme CJ, Montaner JSG, Hull M, Harris M, Niikura M, Brockman MA, Brumme ZL.

Colwill K, Galipeau Y, Stuible M, Gervais C, Arnold C, Rathod B, Abe KT, Wang JH, Pasculescu A, Maltseva M, Rocheleau L, Pelchat M, Fazel-Zarandi M, Iskilova M, Barrios-Rodiles M, Bennett L, Yau K, Cholette F, Mesa C, Li AX, Paterson A, Hladunewich MA, Goodwin PJ, Wrana JL, Drews SJ, Mubareka S, McGeer AJ, Kim J, Langlois M-A, Gingras A-C, Durocher Y. A scalable serology solution for profiling humoral immune responses to SARS-CoV-2 infection and vaccination. Clin Transl Immunol 2022 Mar 23. doi: 10.1002/cti2.1380.

Nikiforuk AM, McMillan B, Bartlett SR, Márquez AC, Pidduck T, Kustra J, Goldfarb DM, Barakauskas V, Sinclair G, Patrick DM, Sadarangani M, Ogilvie GS, Krajden M, Morshed M, Sekirov I, Jassem AN. Performance of Immunoglobulin G Serology on Finger Prick Capillary Dried Blood Spot Samples to Detect a SARS-CoV-2 Antibody Response. Microbiol Spectr. 2022 Mar 10:e0140521. doi: 10.1128/spectrum.01405-21.

Oliver MJ, Thomas D, Balamchi S, Ip J, Naylor K, Dixon SN, McArthur E, Kwong J, Perl J, Atiquzzaman M, Singer J, Yeung A, Hladunewich M, Yau K, Garg AX, Leis JA, Levin A, Krajden M, and Blake PG. Vaccine Effectiveness Against SARS-CoV-2 Infection and Severe Outcomes in the Maintenance Dialysis Population in Ontario, Canada. JASN March 2022, ASN.2021091262; doi: https://doi.org/10.1681/ASN.2021091262.

Grunau B, Golding L, Prusinkiewicz MA, Asamoah-Boaheng M, Armour R, Citlali Marquez A, Jassem AN, Barakauskas V, O’Brien SF, Drews SJ, Haig S, Lavoie PM, Goldfarb DM. Comparative 6-month Wild-Type and Delta-Variant Antibody levels and Surrogate Neutralization for Adults Vaccinated with BNT162b2 vs. mRNA-1273. Microbiol Spectr 2022 Mar 7:e0270221. doi: 10.1128/spectrum.02702-21.

Asamoah-Boaheng M, Goldfarb D, Prusinkiewicz M, Golding L, Karim M, Barakauskas V, Wall N, Jassem A, Marquez A, MacDonald C, O’Brien S, Lavoie P, Grunau B. Determining the optimal SARS-CoV-2 mRNA vaccine dosing interval for maximum immunogenicity. bioRxiv 2022.03.01.482592; doi: https://doi.org/10.1101/2022.03.01.482592

Walmsley S, Szadkowski L, Wouters B, Clarke R, Colwill K, Rochon P, Brudno M, Ravindran R, Raboud J, McGeer A, Oza A. Safety and Efficacy of Preventative COVID Vaccines: The StopCoV Study. MedRxiv. 2022 Feb 10. doi: 10.1101/2022.02.09.22270734v1.

Tang X, Sharma A, Pasic M, Brown P, Colwill K, Gelband H, Birnboim HC, Nagelkerke N, Bogoch II, Bansal A, Newcombe L, Slater J, Rodriguez PS, Huang G, Fu SH, Meh C, Wu CN, Kaul R, Langlois MA, Morawski E, Hollander A, Eliopoulos D, Aloi B, Lam T, Abe KT, Rathod B, Fazel-Zarandi M, Wang J, Iskilova M, Pasculescu A, Caldwell L, Barrios-Rodiles M, Mohammed-Ali Z, Vas N, Santhanam DR, Cho ER, Qu K, Jha S, Jha V, Suraweera W, Malhotra V, Mastali K, Wen R, Sinha S, Reid A, Gingras AC, Chakraborty P, Slutsky AS, Jha P. Assessment of SARS-CoV-2 Seropositivity During the First and Second Viral Waves in 2020 and 2021 Among Canadian Adults. JAMA Network Open. 16 Feb 2022; 5(2):e2146798. doi: 10.1001/jamanetworkopen.2021.46798.

Hall VG, Ferreira V, Ierullo M, Ku T, Majchrzak-Kita B, Kulasingam V, Humar A, Kumar D. Delayed-interval BNT162b2 mRNA COVID-19 vaccination enhances humoral immunity and induces robust T cell responsesNat Immunol (2022). doi: https://doi.org/10.1038/s41590-021-01126-6.

Yau K, Chan CT, Abe KT, Jiang Y, Atiquzzaman M, Mullin SI, Shadowitz E, Liu L, Kostadinovic E, Sukovic T, Gonzalez A, McGrath-Chong ME, Oliver MJ, Perl J, Leis JA, Bolotin S, Tran V, Levin A, Blake PG, Colwill K, Gingras AC and Hladunewich MA. Differences in mRNA-1273 (Moderna) and BNT162b2 (Pfizer-BioNTech) SARS-CoV-2 vaccine immunogenicity among patients undergoing dialysis. CMAJ February 03, 2022 cmaj.211881; DOI: https://doi.org/10.1503/cmaj.211881

Ings DP, Hatfield KM, Fifield KE, Harnum DOA, Holder KA, Russell RS, Grant MD. Few SARS-CoV-2 infections detected in Newfoundland and Labrador in the absence of Public Health Laboratory-based confirmation. PloS One. 2022 Jan 28;17(1):e0262957. Doi: 10.1371/journal.pone.0262957.

Dayam RM, Law JC, Goetgebuer RL, Chao GYC, Abe KT, Sutton M, Finkelstein N, Stempak JM, Pereira D, Croitoru D, Acheampong L, Rizwan S, Rymaszewski K, Milgrom R, Ganatra D, Batista NV, Girard M, Lau I, Law R, Cheung MW, Rathod B, Kitaygorodsky J, Samson R, Hu Q, Haroon N, Inman RD, Piguet V, Chandran V, Silverberg MS, Gingras AC, Watts TH. Antibody and T cell responses to SARS-CoV-2 mRNA vaccines during maintenance therapy for immune-mediated inflammatory diseases. medRxiv 2022.01.26.22269856; doi: https://doi.org/10.1101/2022.01.26.22269856

Widdifield J, Eder L, Chen S, Kwong JC, Hitchon C, Lacaille D, Aviña-Zubieta JA, Svenson LW, Bernatsky S. COVID-19 Vaccination Uptake among individuals with Immune-Mediated Inflammatory Diseases in Ontario, Canada between December 2020 and October 2021: A population-based analysis. J Rheumatol. 2022 Jan 15:jrheum.211148. doi: 10.3899/jrheum.211148.

Zhang A, Breznik JA, Clare R, Nazy I, Miller MS, Bowdish DME, Costa AP. Antibody Responses to Third-Dose mRNA Vaccines in Nursing Home and Assisted Living Residents. J Am Med Dir Assoc. 2022 Jan 15:S1525-8610(21)01109-9. doi: 10.1016/j.jamda.2021.12.035.

Hall V, Ferreira V, Ierullo M, Ku T, Majchrzak-Kita B, Kulasingam V, Humar A, Kumar D. Delayed interval BNT162b2 mRNA COVID-19 vaccination provides robust immunity. 2021, Nature Immunology.

Nasreen S, Calzavara A, Buchan SA, Thampi N, Johnson C, Wilson SE, Kwong JC. Background incidence rates of adverse events of special interest related to COVID-19 vaccines in Ontario, Canada, 2015 to 2020, to inform COVID-19 vaccine safety surveillance. medRxiv. 2022 Jan 16. Doi: 10.1101/2022.01.12.22269169.

Banerjee A, Lew J, Kroeker A, Baid K, Aftanas P, Nirmalarajah K, Maguire F, Kozak R, McDonald R, Lang A, Gerdts V, Straus SE, Gilbert L, Li AX, Mozafarihasjin M, Walmsley S, Gingras AC, Wrana JL, Mazzulli T, Colwill K, McGeer AJ, Mubareka S, Falzarano D. Immunogenicity of convalescent and vaccinated sera against clinical isolates of ancestral SARS-CoV-2, beta, delta, and omicron variants. bioRxiv. 2022 Jan 13. Doi: 10.1101/2022.01.13.475409

Kronfi N, Dussault C, Maheu-Giroux M, Halavrezos A, Chalifoux S, Sherman J, Park, H, Del Balso L, Cheng MP, Poulin S, Cox J. Seroprevalence and Risk Factors for SARS-CoV-2 Among Incarcerated Adult Men in Quebec, Canada (2021), Clinical Infectious Diseases, 2022; ciac031, https://doi.org/10.1093/cid/ciac031

Mwimanzi FM, Lapointe HR, Cheung PK, Sang Y, Yaseen F, Umviligihozo G, Kalikawe R, Datwani S, Omondi HF, Burns L, Young L, Leung V, Ennis S, Agafitei O, Basra S, Lim LY, Ng K, Pantophlet R, Brumme CJ, Montaner JSG, DeMarco M, Holmes D., Simons J, Niikura M, Romney MG, Brumme ZL, Brockman MA. Older Adults Mount Less Durable Humoral Responses to a Two-dose COVID-19 mRNA Vaccine Regimen, but Strong Initial Responses to a Third Dose. medRxiv. 2022 Jan 06. doi: 10.1101/2022.01.06.22268745

Zhang A, Breznik JA, Clare R, Nazy I, Miller MS, Bowdish DME, Costa AP, COVID-in-LTC Study Group. Antibody Responses to 3rd Dose mRNA Vaccines in Nursing Home and Assisted Living Residents. MedRxiv, December 2021. doi: https://doi.org/10.1101/2021.12.17.21267996

Buchan SA, Chung H, Brown KA, Austin PC, Fell DB, Gubbay J, Nasreen S, Schwartz KL, Sundaram ME, Tadrous M, Wilson K, Wilson SE, Kwong J. Effectiveness of COVID-19 vaccines against Omicron or Delta infection. MedRxiv 2021. doi: https://doi.org/10.1101/2021.12.30.21268565

Duarte N, Yanes-Lane M, Arora RK, Bobrovitz N, Liu M, Bego MG, Yan T, Cao C, Gurry C, Hankins CA, Cheng MP, Gingras AC, Mazer BD, Papenburg J, Langlois MA, Adapting serosurveys for the SARS-CoV-2 vaccine eraOpen Forum Infectious Diseases, 2021; ofab632, https://doi.org/10.1093/ofid/ofab632

Kim GN, Choi JA, Wu K, Saeedian N, Yang E, Park H, Woo SJ, Lim G, Kim SG, Eo SK, Jeong HW, Kim, T, Chang JH, Seo SH, Kim NH, Choi E, Choo S, Lee S, Winterborn A, Li Y, Parham K, Donovan JM, Fenton B, Dikeakos JD, Dekaban GA, Haeryfar SMM, Troyer RM, Arts EJ, Barr SD, Song M, Kang CY. A vesicular stomatitis virus-based prime-boost vaccination strategy induces potent and protective neutralizing antibodies against SARS-CoV-2. PLoS Pathogens. 2021 Dec 16;17(12):e1010092. doi: 10.1371/journal.ppat.1010092

Nasreen S, Calzavara AJ, Sundaram ME, MacDonald, SE, Righolt CH, Pai M, Field TS, Zhou LW, Wilson SE, Kwong JC, Background incidence rates of hospitalisations and emergency department visits for thromboembolic and coagulation disorders in Ontario, Canada for COVID-19 vaccine safety assessment: a population-based retrospective observational study. BMJ Open 2021; 11:e052019. doi : 10.1136/bmjopen-2021-052019

Zinszer K, McKinnon B, Bourque N, Pierce L, Saucier A, Otis A,  Cheriet I, Papenburg J, Hamelin ME, Charland K, Carbonneau J, Zahreddine M, Savard A, Fortin G, Apostolatos A, Haley N, Ratté N, Laurin I, Nguyen  CT, Conrod P, Boivin G, De Serres G, Quach C; Seroprevalence of SARS-CoV-2 Antibodies Among Children in School and Day Care in Montreal, Canada. JAMA Network Open 4.11 (2021): e2135975-e2135975.

Bergeri I, Whelan M, Ware H, Subissi L, Nardone A, Lewis HC, Li Z, Ma X, Valenciano M, Cheng B, Al Ariqi L, Rashidian A, Okeibunor J, Azim T, Wijesinghe Le LV, Vaughan A, Pebody R, Vicari A, Yan T, Yanes-Lane M, Cao C, Cheng MP, Papenburg J, Buckeridge D, Bobrovitz N, Arora RK, van Kerkhove MD, Unity Studies Collaborator. Global epidemiology of SARS-CoV-2 infection: a systematic review and meta-analysis of standardized population-based seroprevalence studies, Jan 2020-Oct 2021. GroupmedRxiv 2021.12.14.21267791; doi: https://doi.org/10.1101/2021.12.14.21267791

Cao H, Mai J, Zhou Z, Li Z, Duan R, Watt J, Chen Z, Bandara RA, Li M, Ahn SK, Poon B, Christie-Holmes N, Gray-Owen SD, Banerjee A, Mossman K, Kozak R, Mubareka S, Rini JM, Hu J, Liu J. Intranasal HD-Ad vaccine protects the upper and lower respiratory tracts of hACE2 mice against SARS-CoV-2. Cell Biosci. 2021 Dec 8;11(1):202. doi: 10.1186/s13578-021-00723-0. PMID: 34879865; PMCID: PMC8653804.

Costiniuk CT, Singer J, Langlois M, Kulic I, Needham J, Burchell A, Jenabian M, Walmsley S, Ostrowski M, Kovacs C, Tan D, Harris M, Hull M, Brumme, Z, Brockman M, Margolese S, Mardarino E, Angel JB, Routy JP, Anis AH, Cooper C, CTN 328: immunogenicity outcomes in people living with HIV in Canada following vaccination for COVID-19 (HIV-COV): protocol for an observational cohort study. BMJ Open 2021;11:e054208. doi: 10.1136/bmjopen-2021-054208

Law JC, Girard M, Chao GYC, Ward LA, Isho B, Rathod B, Colwill K, Li Z, Rini JM, Yue FY, Mubareka S, McGeer AJ, Ostrowski MA, Gommerman JL, Gingras A-C, Watts TH. Persistence of T Cell and Antibody Responses to SARS-CoV-2 Up to 9 Months after Symptom Onset. J Immunol. 2021 Dec 13. doi: 10.4049/jimmunol.2100727.

Cholette F, Mesa C, Harris A, Ellis H, Cachero K, Lacap P, Galipeau Y, Langlois M-A, Gingras A-C, Yansouni CP, Papenburg J, Cheng MP, Chakraborty P, Stein DR, Caeseele PV, Bartlett S, Krajden M, Goldfarb D, McGeer A, Osiowy C, Hankins C, Mazer B, Drebot M, Kim J, on behalf of the COVID-19 Immunity Task Force (CITF) working group. Dried blood spot specimens for SARS-CoV-2 antibody testing: A multi-site, multi-assay comparison. PLOS ONE. 2021 Dec 7. doi: 10.1371/journal.pone.0261003

Bettinger JA, De Serres G, Valiquette L, Sadarangani M, Muller MP, Vanderkooi OG, Kellner JD, Top KA, Isenor JE, McGeer A, Irvine M, Shulha H, Marty K. Canadian National Vaccine Safety (CANVAS) Network: Active Safety Surveillance on COVID-19 vaccines. Canadian Immunization Conference. 2021 Dec 8.

Buchan SA, Yon Seo C, Johnson C, Alley S, Kwong JC, Nasreen S, Calzavara A, Lu D, Harris TM, Yu K, Wilson SE. Epidemiology of myocarditis and pericarditis following mRNA vaccines in Ontario, Canada: by vaccine product, schedule and interval. medRxiv. 2021 Dec 05. doi: https://doi.org/10.1101/2021.12.02.21267156

Nasreen S, Calzavara A, Sundaram M, Macdonald SE, Righolt C, Pai M, Field T, Zhou LW, Wilson S, Kwong JC. Background rates of hospitalizations and emergency department visits for selected thromboembolic and coagulation disorders in Ontario, Canada, 2015 to 2020, to inform COVID-19 vaccine safety surveillance. 2021. https://doi.org/10.1101/2021.04.02.21254856

Brockman MA, Mwimanzi F, Lapointe HR, Sang Y, Agafitei O, Cheung P, Ennis S, Ng K, Basra S, Lim LY, Yaseen F, Young L, Umviligihozo G, Omondi FH, Kalikawe R, Burns R, Brumme CJ, Leung V, Montaner JSG, Holmes D, DeMarco ML, Simons J, Pantophlet R, Niikura M, Romney MG, Brumme ZL. Reduced magnitude and durability of humoral immune responses to COVID-19 mRNA vaccines among older adults. J Infect Dis. 2021 Dec 9. Doi: https://doi.org/10.1093/infdis/jiab592

Brunet-Ratnasingham E, Anand SP, Gantner P, Dyachenko A, Moquin-Beaudry G, Brassard N, et al. Integrated immunovirological profiling validates plasma SARS-CoV-2 RNA as an early predictor of COVID-19 mortality. Sci Adv. 2021 Nov 26;7(48):eabj5629. doi: 10.1126/sciadv.abj5629.

Grunau B, Goldfarb DM, Asamoah-Boaheng M, Golding L, Kirkham TL, Demers PA, Lavoie PM. Immunogenicity of extended mRNA SARS-CoV-2 vaccine dosing intervals. JAMA. 2021 Dec 3, 2021. doi: 10.1001/jama.2021.21921

Galipeau Y, Siragam V, Laroche G, Marion E, Greig M, McGuinty M, Booth RA, Durocher Y, Cuperlovic-Culf M, Bennett SAL, Crawley AM, Giguère P, Cooper C, Langlois M-A. Relative Ratios of Human Seasonal Coronavirus Antibodies Predict the Efficiency of Cross-Neutralization of SARS-CoV-2 Spike Binding to ACE2. EBioMedicine 2021 Dec.; doi: doi.org/10.1016/j.ebiom.2021.103700

Brunet-Ratnasingham E, Anand SP, Gantner P, Dyachenko A, Moquin-Beaudry G, Brassard N et coll. Integrated immunovirological profiling validates plasma SARS-CoV-2 RNA as an early predictor of COVID-19 mortality. Sci Adv. November 26, 2021;7(48):eabj5629. doi : 10.1126/sciadv.abj5629.

Bobrovitz N, Noel KC, Li Z, Cao C, Deveaux G, Selemon A, Lane MY, Yan T, Arora RK. SeroTracker-ROB: reproducible decision rules for risk of bias assessment of seroprevalence studies. medRxiv. 2021 Nov 21. doi: https://doi.org/10.1101/2021.11.17.21266471

Choi A, Mâsse L.C., Bardwell S, Zhao Y, Xu YXZ, Markarian A, Coombs D, Watts A, Macdonald A, Dhillon N, Irvine M O’Reilly C, Lavoie PM, Goldfarb D. Symptomatic and asymptomatic transmission of SARS-CoV-2 in K-12 schools, British Columbia, April to June 2021. medRxiv. 2021 Nov 20. doi.org/10.1101/2021.11.15.21266284

Grunau B, Asamoah-Boaheng M, Lavoie PM, Ehsanul Karim M, Kirkham T, Demers PA, Barakauskas V, Citlali Marquez A, Jassem AN, O’Brien SF, Drews SJ, Haig S, Cheskes S, Goldfarb DM. A Higher Antibody Response is Generated with a 6 – 7 Week (vs Standard) SARS-CoV-2 Vaccine Dosing Interval. Clin Infect Dis. 2021 Nov;X(X):ZZ-XX. doi: 10.1093/cid/ciab938.

Shire ZJ, Reicherz F, Lawrence S, Sudan H, Golding L, Majdoubi A, Levett PN, Lavoie PM, Jacobson K. Antibody response to the BNT162b2 SARS-CoV-2 vaccine in paediatric patients with inflammatory bowel disease treated with anti-TNF therapy. Gut. 23 Nov 2021. doi: 10.1136/gutjnl-2021-326196

Ferreira VH, Marinelli T, Ierullo M, Ku T, Hall VG, Majchrzak-Kita B, Kulasingam V, Humar A, Kumar D. SARS-CoV-2 infection induces greater T-cell responses compared to vaccination in solid organ transplant recipients. J Infect Dis. 2021 Nov 5. doi: 10.1093/infdis/jiab542.

McKinnon B, Quach C, Dubé E, Nguyen CT, Zinszer K. Social inequalities in COVID-19 vaccine acceptance and uptake for children and adolescents in Montreal, Canada: a cross-sectional studyVaccinedoi: https://doi.org/10.1016/j.vaccine.2021.10.077

Kronfi N, Dussault C, Maheu-Giroux M, Halavrezos A, Chalifoux S, and Sherman J, Park, H, Del Balso L, Cheng MP, Poulin S, Cox J. Seroprevalence and Risk Factors for SARS-CoV-2 Among Incarcerated Adult Men in Quebec, Canada (2021): A Cross-Sectional Study. Pre-print The Lancet, November 9 2021 Doi: http://dx.doi.org/10.2139/ssrn.3959665

Breznik JA, Zhang A, Huynh A, Miller MS, Nazy I, Bowdish DME, Costa AP, Antibody Responses 3-5 Months Post-Vaccination with mRNA-1273 or BNT163b2 in Nursing Home Residents, JAMDA, DOI: https://doi.org/10.1016/j.jamda.2021.10.001

MacDonald C, Demers PA, Grunau B, Goldfarb D, O’Neill D, Armour R, Kirkham TL; Mental Health and Life Satisfaction Among Canadian Paramedics during the COVID-19 Pandemic.

Madathil S, Siqueira WL, Marin LM, Sanaulla FB, Faraj N, Quiñonez CR, et al. The incidence of COVID-19 among dentists practicing in the community in Canada: A prospective cohort study over a six-month period. The Journal of the American Dental Association. J Am Dent Assoc; 2021; DOI: https://doi.org/10.1016/j.adaj.2021.10.006

Fu Z, Rais, Y, Drabovich AP. Immunoprecipitation-targeted proteomics assays facilitate rational development of SARS-CoV-2 serological diagnostics. medRxiv. 25 Oct 2021. doi: 10.1101/2021.10.25.21265408v1

Drews SJ, Abe KT, Hu Q, Samson R, Gingras AC, Colwill K, Rathod B, Wang J, Fazel‐Zarandi M, Yi QL, Robinson A. Resistance of SARS‐CoV‐2 Beta and Gamma variants to plasma collected from Canadian blood donors during the Spring of 2020Transfusion. 2021 Oct 18. doi: 10.1111/trf.16713

Colwill K, Galipeau Y, Stuible M, Gervais C, Arnold C, Rathod B, Abe KT, Wang JH, Pasculescu A, Maltseva M, Rocheleau L, Pelchat M, Fazel-Zarandi M, Iskilova M, Barrios-Rodiles M, Bennett L, Yau K, Cholette F, Mesa C, Li AX, Paterson A, Hladunewich MA, Goodwin PJ, Wrana JL, Drews SJ, Mubareka S, McGeer AJ, Kim J, Langlois M-A, Gingras A-C, Durocher Y. A “Made-in-Canada” serology solution for profiling humoral immune responses to SARS-CoV-2 infection and vaccinationbioRxiv. 2021 Oct 26. doi: 10.1101/2021.10.25.21265476v1

Demone JJ, Maltseva M, Nourimand M, Nasr-Sharif M, Galipeau Y, Langlois MA, MacLean AM. Plant-based production of SARS-CoV-2 antigens for use in a subunit vaccine. bioRxiv. 2021 Jan 1. doi: 10.1101/2021.10.17.464700

Mithani SS, Bota AB, Zhu DT, Wilson K. A scoping review of global vaccine certificate solutions for COVID-19. Hum Vaccin Immunother. 2021 Oct 6.  doi:10.1080/21645515.2021.1969849

Brumme ZL, Mwimanzi F, Lapointe HR, Cheung P, Sang Y, Duncan MC, Yaseen F, Agafitei O, Ennis S, Ng K, Basra S, Lim LY, Kalikawe R, Speckmaier S, Moran-Garcia N, Young L, Ali H, Ganase B, Umviligihozo G, Omondi FH, Atkinson K, Sudderuddin H, Toy J, Sereda P, Burns L, Costiniuk CT, Cooper C, Anis AH, Leung V, Holmes D, DeMarco ML, Simons J, Hedgcock M, Romney MG, Barrios R, Guillemi S, Brumme CJ, Pantophlet R, Montaner JSG, Niikura M, Harris M, Hull M, Brockman MA. Humoral immune responses to COVID-19 vaccination in people living with HIV on suppressive antiretroviral therapy. medRxiv. 2021 Oct 4. doi: https://doi.org/10.1101/2021.10.03.21264320

Merkley E, Loewen PJ. Assessment of Communication Strategies for Mitigating COVID-19 Vaccine-Specific Hesitancy in CanadaJAMA Netw Open. 2021 Sep 1;4(9):e2126635. doi: 10.1001/jamanetworkopen.2021.26635

Saeed S, O’Brien SF, Abe K, Yi O, Rathod B, Wang J, Fazel-Zarandi M, Tuite A, Fisman D, Wood H, Colwill K, Gingras A-C, Drews S. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence: Navigating the absence of a gold standard. PLOS ONE. 2021 Sep 23. doi: https://doi.org/10.1371/journal.pone.0257743

Ayoubkhani D, Pawelek P, Gaughan C. Technical article: Updated estimates of the prevalence of post-acute symptoms among people with coronavirus (COVID-19) in the UK: 26 April 2020 to 1 August 2021. UK Office for National Statistics. Released: 16 September 2021

SARS-CoV-2–Reactive Mucosal B Cells in the Upper Respiratory Tract of Uninfected Individuals. J Immunol October 4, 2021, ji2100606; DOI: https://doi.org/10.4049/jimmunol.2100606

Antia R, Halloran ME. Transition to endemicity: Understanding COVID-19, Immunity (2021). Immunity, 24 september 2021 doi: 10.1016/j.immuni.2021.09.019

Vinh DC, Gouin JP, Cruz-Santiago D, Canac-Marquis M, Bernier S, Bobeuf F, Sengupta A, Brassard JP, Guerra A, Dziarmaga R, Perez A, Sun Y, Li Y, Roussel L, Langelier J, Ke D, Arnoldd C, Pelchat M, Langlois MA, Zhang X, Mazer BD. Real-world serologic responses to Extended-interval and Heterologous COVID-19 mRNA vaccination in Frail Elderly-Interim report from a prospective observational cohort study. medRxiv 21 Sept 2021; doi: 10.1101/2021.09.16.21263704

Luong L, Beder M, Nisenbaum R, Orkin A, Wong J, Damba C, Emond R, Lena S, Wright V, Loutfy M, Bruce-Barrett C, Cheung W, Cheung YK, Williams V, Vanmeurs M, Boozary A, Manning H, Hester J, Hwang SW, 2021. Prevalence of SARS-CoV-2 infection among people experiencing homelessness in Toronto during the first wave of the COVID-19 pandemic. medRxiv, September 26, 2021. doi:10.1101/2021.09.21.21263713

Saeed S, O’Brien SF, Abe K, Yi O, Rathod B, Wang J, Fazel-Zarandi M, Tuite A, Fisman D, Wood H, Colwill K, Gingras A-C, Drews S. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence: Navigating the absence of a gold standard. PLOS ONE. 2021 Sep 23. doi: https://doi.org/10.1371/journal.pone.0257743

Skowronski DM, Setayeshgar S, Zou M, Prystajecky N, Tyson JR, Sbihi H, Fjell CD, Galanis E, Naus M, Patrick DM, El Adam S. Comparative single-dose mRNA and ChAdOx1 vaccine effectiveness against SARS-CoV-2, including early variants of concern: a test-negative design, British Columbia, Canada. medRxiv. 2021 Sept 22. doi : 10.1101/2021.09.20.21263875

Yanling Liu, Patrick Budylowski, Shilan Dong, Zhijie Li, Sofiya Goroshko, Leslie Y. T. Leung, Eyal Grunebaum, Paolo Campisi, Evan J. Propst, Nikolas E. Wolter, James M. Rini, Amin Zia, Mario Ostrowski and Götz R. A. Ehrhardt. SARS-CoV-2–Reactive Mucosal B Cells in the Upper Respiratory Tract of Uninfected Individuals. J Immunol October 4, 2021, ji2100606; DOI: https://doi.org/10.4049/jimmunol.2100606

Vinh DC, Gouin JP, Cruz-Santiago D, Canac-Marquis M, Bernier S, Bobeuf F, Sengupta A, Brassard JP, Guerra A, Dziarmaga R, Perez A, Sun Y, Li Y, Roussel L, Langelier J, Ke D, Arnoldd C, Pelchat M, Langlois MA, Zhang X, Mazer BD. Real-world serologic responses to Extended-interval and Heterologous COVID-19 mRNA vaccination in Frail Elderly-Interim report from a prospective observational cohort study. medRxiv 21 Sept 2021;doi: 10.1101/2021.09.16.21263704

Saeed S, O’Brien SF, Abe K, Yi O, Rathod B, Wang J, Fazel-Zarandi M, Tuite A, Fisman D, Wood H, Colwill K, Gingras A-C, Drews S. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence: Navigating the absence of a gold standard. PLOS ONE. 2021 Sep 23. doi: https://doi.org/10.1371/journal.pone.0257743

Tang, X., Gelband, H., Nagelkerke, N., Bogoch, I.I., Brown, P., Morawski, E., Tam, T., 2021. COVID-19 vaccination intention during early vaccine rollout in Canada: a nationwide online surveyThe Lancet Regional Health – Americas 100055. doi: 10.1016/j.lana.2021.100055

Dick DW, Childs L, Feng Z, Li J, Röst G, Buckeridge DL, Ogden NH, Heffernan JM. Fall 2021 Resurgence and COVID-19 Seroprevalence in Canada Modelling waning and boosting COVID-19 immunity in Canada A Canadian Immunization Research Network Study. medRxiv 2021.08.17.21262188; doi: https://doi.org/10.1101/2021.08.17.21262188

Hogan CA, Jassem AN, Sbihi H, Joffres Y, Tyson JR, Noftall K, Taylor M, Lee T, Fjell C, Wilmer A, Galbraith J, Romney MG, Henry B, Krajden M, Galanis E, Prystajecky N, Hoang LMN. Rapid Increase in SARS-CoV-2 P.1 Lineage Leading to Codominance with B.1.1.7 Lineage, British Columbia, Canada, January-April 2021. Emerg Infect Dis. 2021 Aug 13;27(11). doi: 10.3201/eid2711.211190

Rais Y, Fu Z, Drabovich AP. Mass spectrometry-based proteomics in basic and translational research of SARS-CoV-2 coronavirus and its emerging mutants. Clin Proteomics. 2021. 18:19. Doi: 10.1186/s12014-021-09325-x

Breznik JA, Zhang A, Huynh A, Miller MS, Nazy I, Bowdish DME, Costa AP, COVID-in-LTC Study Group. Antibody responses 3-5 months post-vaccination with mRNA-1273 or BNT163b2 in nursing home residents. medRxiv. 19 Aug 2021. Doi: https://doi.org/10.1101/2021.08.17.21262152

Tang X, Sharma A, Pasic M, Brown P, Colwill K, Gelband H, Birnboim HC, Nagelkerke N, Bogoch II, Bansal A, Newcombe L, Slater J, Rodriguez PS, Huang G, Fu SH, Meh C, Wu CN, Kaul R, Langlois MA, Morawski E, Hollander A, Eliopoulos D, Aloi B, Lam T, Abe KT, Rathod B, Fazel-Zarandi M, Wang J, Iskilova M, Pasculescu A, Caldwell L, Barrios-Rodiles M, Mohammed-Ali Z, Vas N, Santhanam DR, Cho ER, Qu K, Jha S, Jha V, Suraweera W, Malhotra V, Mastali K, Wen R, Sinha S, Reid A, Gingras AC, Chakraborty P, Slutsky AS, Jha P. SARS-CoV-2 Seroprevalence During the First and Second Pandemic Waves in Canada. SSRN. 12 Aug 2021. Doi: http://dx.doi.org/10.2139/ssrn.3903944

Lee BE, Sikora C, Faulder D, Risling E, Little LA, Qiu Y, Gao T, Bulat R, Craik S, Hrudey SE, Ohinmaa A, Estabrooks C, Gingras AC, Charlton C, Kim J, Wood H, Robinson A, Kanji JN, Zelyas N, O’Brien SF, Drews S, Pang XL. Early Warning and Rapid Public Health Response to Prevent COVID-19 outbreaks in long-term care facilities (LTCF) by Monitoring SARS-CoV-2 RNA in LTCF site-specific Sewage Samples and Assessment of Antibodies Response in this Population – Prospective Study Protocol. BMJ Open August 20 2021;11(8):e052282. doi : 10.1136/bmjopen-2021-052282.

Sheikh-Mohamed S, Chao GYC, Isho B, Zuo M, Nahass GR, Salomon-Shulman RE, Blacker G, Fazel-Zarandi M, Rathod B, Colwill K, Jamal A, Li Z, Quin de Launay K, Takaoka A, Garnham-Takaoka J, Fahim C, Paterson A, Xinliu Li A, Haq N, Barati S, Gilbert L, Green K, Mozafarihashjin M, Samaan P, Siqueira W, Mubareka S, Ostrowski M, Rini JM, Rojas OL, McGeer A, Weissman IL, Caspi Tal M, Straus S, Gingras AC, Gommerman JL. A mucosal antibody response is induced by intra-muscular SARS-CoV-2 mRNA vaccination. medRxiv 2021.08.01.21261297; doi: https://doi.org/10.1101/2021.08.01.21261297

Abe KT, Hu Q, Mozafarihashjin M, Samson B, Rathod B, Chao G, Wang JH, Iskilova M, Pasculescu A, Fazel-Zarandi M, Li A, Paterson A, Green K, Gilbert L, Barati S, Haq N, Takaoka A, Takaoka JG, De Launay KQ, Fahim C, Sheikh-Mohamed S, Arita Y, Durocher Y, Marcusson EG, Gommerman JL, Ostrowski M, Colwill K, Straus SE, Wood H, McGeer AJ, Gingras AC. Neutralizing antibody responses to SARS-CoV-2 variants in vaccinated Ontario long-term care home residents and workers. MedRxiv. 2021 Aug 8. doi: https://www.medrxiv.org/content/10.1101/2021.08.06.21261721v1

Nikiforuk AM, McMillan B, Bartlett SR,  Márquez AC, Pidduck T,  Kustra J,  Goldfarb DM, Barakauskas V, Sinclair G,  Patrick DM,  Sadarangani M, Ogilvie GS, Morshed M, Sekirov, Jassem AN. Performance of Immunoglobulin G Serology on Finger Prick Capillary Dried Blood Spot Samples to Measure SARS-CoV-2 Seroconversion and Humoral Immunogenicity of COVID-19 Vaccination. medRxiv. July 31 2021. doi: https://doi.org/10.1101/2021.07.29.21261156

Khana MS, Allison PJ, Siqueira WL, McNally ME, Glogauer M, Quinonez C, Madathil SA. Prevalence of COVID-19 among Canadian Dentists in August 2020. Poster #1917, presented at 99th International Association for Dental Research (IADR) General Session conference. July 21-24, 2021.

Seth R, Allison PJ, Siqueira WL, McNally ME, Quinonez C, Glogauer M, Madathil SA. COVID-19 Anxiety syndrome among Canadian dentists during the pandemic. Poster #1918, presented at 99th International Association for Dental Research (IADR) General Session conference. July 21-24, 2021.

Hall VG, Ferreira VH, Ierullo M, Ku T, Marinelli T, Majchrzak-Kita B, Yousuf A, Kulasingam V, Humar A, Kumar D. Humoral and Cellular immune response and Safety of 2-dose SARS-CoV-2 mRNA-1273 (Moderna) vaccine in Solid Organ Transplant Recipients. Am J Transplant. 2021 August 00:1-10 doi: 10.1111/ajt.16766

Li, X., Vanderloo, L.M., Maguire, J.L., Keown-Stoneman, C.D.G., Aglipay, M., Anderson, L.N., Cost, K.T., Charach, A., Vanderhout, S.M., Birken, C.S., TARGet Kids! Collaboration, 2021. Public health preventive measures and child health behaviours during COVID-19: a cohort study. Canadian Journal of Public Health. doi:10.17269/s41997-021-00549-w

Britt McKinnon, Caroline Quach, Ève Dubé, Cat Tuong Nguyen, Kate Zinszer. Social inequalities in COVID-19 vaccine acceptance and uptake for children and adolescents in Montreal, Canada: a cross-sectional study doi: https://doi.org/10.1101/2021.05.08.21256831

Chantal Williams, MSc, Dana Al-Bargash, MSc, Celeste Macalintal, RN, BScN, Rebecca Stuart, MSc, Anu Seth, RN, BScN, Julienne Latham, RN, Leah Gitterman, MHSc, Stephanie Fedsin, NP, Marion Godoy, RN, BScN, Robert Kozak, PhD, Jennifer L Guthrie, PhD, Heidi Wood, PhD, Allison McGeer, MD, Susy Hota, MD, Elizabeth Rea, MD. COVID-19 Outbreak Associated with a SARS-CoV-2 P. 1 Lineage in a Long-Term Care Home after Implementation of a Vaccination Program–Ontario, April-May 2021. Clinical Infectious Diseases. 2021 Jul 8. DOI: https://doi.org/10.1093/cid/ciab617

Galipeau Y, Siragam V, Laroche G, Marion E, Greig M, McGuinty M, Booth RA, Durocher Y, Cuperlovic-Culf M, Bennett SAL, Crawley AM, Giguère P, Cooper C, Langlois M-A. Relative Ratios of Human Seasonal Coronavirus Antibodies Predict the Efficiency of Cross-Neutralization of SARS-CoV-2 Spike Binding to ACE2. MedRxiv 2021.07.16.21260079; doi: https://doi.org/10.1101/2021.07.16.21260079

Duarte N, D’Mello S, Duarte NA, Rocco S, Wyk JV, Pillai AA, Liu M, Williamson T, Arora RK. Uptake of SARS-CoV-2 workplace testing programs, March 2020 to March 2021.

Nasreen S, He S, Chung H, Brown KA, Gubbay JB, Buchan SA, Wilson SE, Sundaram ME, Fell DB, Chen B, Calzavara A, Austin PC, Schwartz KL, Tadrous M, Wilson K, Kwong JC. Effectiveness of COVID-19 vaccines against variants of concern, Canada.

Bobrovitz N, Arora RK, Cao C, Boucher E, Liu M, Donnici C, Yanes-Lane M, Whelan M, Perlman-Arrow S, Chen J, Rahim H, Ilincic N, Segal M, Duarte N, Van Wyk J, Yan T, Atmaja A, Rocco S, Joseph A, Penny L, Clifton DA, Williamson T, Yansouni CP, Evans TG, Chevrier J, Papenburg J, Cheng MP. Global seroprevalence of SARS-CoV-2 antibodies: A systematic review and meta-analysis. PLOS ONE. 16(6): e0252617. doi: 10.1371/journal.pone.0252617.

Costa AP, Manis DR, Jones A, Stall NM, Brown KA, Boscard V, Castellino A, Heckman GA, Hillmer MP, Ma C, Pham P, Rais S, Sinha SK, Poss JW. Facteurs de risque d’éclosion de SRAS-CoV-2 dans les résidences pour aînés en Ontario, au Canada: étude de cohorte à l’échelle de la population. JAMC. 2021 Jun 21;193(25):E969-77. doi: 10.1503/cmaj.202756-f.

Goldfarb DM, Mâsse LC, Watts AW, Hutchison SM, Muttucomaroe L, Bosman ES, Barakauskas VE, Choi A, Irvine MA, Reicherz F, Coombs D, O’Reilly C, Sediqi S, Razzaghian HR, Sadarangani M, O’Brien SF, Lavoie PM. SARS-CoV-2 seroprevalence among Vancouver public school staff in British Columbia, Canada. medRxiv. 2021 Jun 18. doi: 10.1101/2021.06.16.21258861.

Law JC, Girard M, Chao GYC, Ward LA, Isho B, Rathod B, Colwill K, Li Z, Rini JM, Yue FY, Mubareka S, McGeer AJ, Ostrowski MA, Gommerman JL, Gingras A-C, Watts TH. Immunity to SARS-CoV-2 persists 9 months post-symptoms with an altered T cell phenotype compared to influenza A virus-specific memory. medRxiv. 2021 Jun 10. doi: 10.1101/2021.06.08.21258518.

Matic N, Lowe CF, Ritchie G, Stefanovic A, Lawson T, Jang W, Young M, Dong W, Brumme ZL, Brumme CJ, Leung V, Romney MG. Rapid detection of SARS-CoV-2 variants of concern identifying a cluster of B.1.1.28/P.1 variant in British Columbia, Canada. Emerg Infect Dis. 2021 Jun;27(6):1673-1676. doi: 10.3201/eid2706.210532.

Chung H, He S, Nasreen S, Sundaram ME, Buchan SA, Wilson SE, Chen B, Calzavara A, Fell DB, Austin PC, Wilson K, Schwartz KL, Brown KA, Gubbay JB, Basta NE, Mahmud SM, Righolt CH, Svenson LW, Macdonald SE, Janjua NZ, Tadrous M, Kwong JC. Effectiveness of BNT162b2 and mRNA-1273 COVID-19 vaccines against symptomatic SARS-CoV-2 infection and severe COVID-19 outcomes in Ontario, Canada. 2021 May 28. doi: 10.1101/2021.05.24.21257744.

Saeed S, O’Brien SF, Abe K, Yi O, Rathod B, Wang J, Fazel-Zarandi M, Tuite A, Fisman D, Wood H, Colwill K, Gingras A-C, Drews S. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence: Navigating the absence of a gold standard. medRxiv. 2021 May 12. doi: 10.1101/2021.05.11.21256992.

Anand SP, Prévost J, Nayrac M, Beaudoin-Bussières G, Benlarbi M, Gasser R, Brassard N, Laumaea A, Gong SY, Bourassa C, Brunet-Ratnasingham E, Medjahed E, Gendron-Lepage G, Goyette G, Gokool L, Morrisseau C, Bégin P, Martel-Laferrière V, Tremblay C, Richard J, Bazin R, Duerr R, Kaufmann D, Finzi A.  Longitudinal analysis of humoral immunity against SARS-CoV-2 Spike in convalescent individuals up to 8 months post-symptom onset. Cell Rep Med. 2021 May 4. doi: 10.1016/j.xcrm.2021.100290.

Tang X, Gelband H, Nagelkerke N, Bogoch I, Brown PE, Morawski E, Lam T, Reid A, Jha P. Quantifying COVID-19 vaccination hesitancy during early vaccination rollout in Canada. medRxiv [Preprint]. 2021 May 2. doi: 10.1101/2021.04.29.21256333.

Flood CM, Thomas B, Wilson K. Vaccination obligatoire des travailleurs de la santé: analyse juridique et politique. CMAJ. 2021 Apr 26;193(17):E629-33. doi: 10.1503/cmaj.202755-f.

Huynh A, Arnold DM, Smith JW, Moore JC, Zhang A, Chagla Z, Harvey BJ, Stacey HD, Ang JC, Clare R, Ivetic N, Chetty VT, Bowdish DME, Miller MS, Kelton JG, Nazy I. Characteristics of anti-SARS-CoV-2 antibodies in recovered COVID-19 subjects. Viruses. 2021 Apr 16;13(4):697. doi: 10.3390/v13040697.

Zinszer K, McKinnon B, Bourque N, Zahreddine M, Charland K, Papenburg J, Fortin G, Hamelin ME, Saucier A, Apostolatos A, Pierce L, Savard-Lamothe A, Carbonneau J, Conrod P, Haley N, Laurin I, Boivin G, Serres GD, Quach C. Seroprevalence of anti-SARS-CoV-2 antibodies among school and daycare children and personnel: protocol for a cohort study in Montreal, Canada. BMJ Open. 2021;11:e053245. doi:10.1136/bmjopen-2021-053245.

Brockman MA, Mwimanzi F, Sang Y, Ng K, Agafitei O, Ennis S, Lapointe H, Young L, Umviligihozo G, Burns L, Brumme CJ, Leung V, Montaner JSG, Holmes D, DeMarco M, Simons J, Niikura M, Pantophlet R, Romney MG, Brumme ZL. Weak humoral immune reactivity among elderly residents of long-term care facilities following one dose of BNT162b2 mRNA COVID-19 vaccine. medRxiv [Preprint]. 2021 Mar 24. doi: 10.1101/2021.03.17.21253773

Irfan Ullah, Jérémie Prévost, Mark S Ladinsky, Helen Stone, Maolin Lu, Sai Priya Anand, Guillaume Beaudoin-Bussières, Mehdi Benlarbi, Shilei Ding, Romain Gasser, Corby Fink, Yaozong Chen, Alexandra Tauzin, Guillaume Goyette, Catherine Bourassa, Halima Medjahed, Matthias Mack, Kunho Chung, Craig B Wilen, Gregory A. Dekaban, Jimmy D. Dikeakos, Emily A. Bruce, Daniel E Kaufmann, Leonidas Stamatatos, Andrew T. McGuire, Jonathan Richard, Marzena Pazgier, Pamela J. Bjorkman, Walther Mothes, Andrés Finzi, Priti Kumar, Pradeep D. Uchil. Live imaging of SARS-CoV-2 infection in mice reveals neutralizing antibodies require Fc function for optimal efficacy. bioRxiv [Preprint]. 2021 Mar 22. doi: 10.1101/2021.03.22.436337

Brunet-Ratnasingham E, Anand SP, Gantner P, Moquin-Beaudry G, Dyachenko A, Brassard N, Beaudoin-Bussières G, Pagliuzza A, Gasser R, Benlarbi M, Point F, Prévost J, Laumaea A, Niessl J, Nayrac M, Sannier G, Boutin M, Descôteux-Dinelle J, Gendron-Lepage G, Goyette G, Bourassa C, Medjahed H, Orban C, Butler-Laporte G, Morrison D, Zhou S, Nakanishi T, Laurent L, Richard J, Dubé M, Fromentin R, Rébillard R-M, Arbour N, Prat A, Larochelle C, Durand M, Richards JB, Chassé M, Tétreault M, Chomont N, Finzi A, Kaufmann DE. Integrated immunovirological profiling validates plasma SARS-CoV-2 RNA as an early predictor of COVID-19 mortality. medRxiv [Preprint]. 2021 Mar 20. doi: 10.1101/2021.03.18.21253907

Majdoubi A, Michalski C, O’Connell SE, Dada S, Narpala S, Gelinas J, Mehta D, Cheung C, Winkler D, Basappa M, Liu  AC, Görges M, Barakauska VE, Irvine M, Mehalko J, Esposito D, Sekirov I, Jassem AN, Goldfarb DM, Pelech S, Douek DC, McDermott AB, Lavoie PM. A majority of uninfected adults show pre-existing antibody reactivity against SARS-CoV-2. JCI Insight. 2021 Mar 15. doi: 10.1172/jci.insight.146316.

Castonguay N, Zhang W, Langlois M-A. Meta-analysis of the dynamics of the emergence of mutations and variants of SARS-CoV-2. medRxiv [Preprint]. 2021 Mar 8. doi: 10.1101/2021.03.06.21252994

Tang X, Sharma A, Pasic M, Colwill K, Birnboim Ch, Nagelkerke Nico, Bogoch I, Schultz C, Newcombe L, Slater J, Rodriguez P, Huang G, Fu SH,  Meh C, Wu ChN,  Kaul R, Langlois MA, M E, Hollander A, Eliopoulos D, Aloi B, Lambe T, AbeK, Caldwell L, Barrios-Rodiles M,  Fazel-Zarandi M, Weingust R, Wang J, Rathod B, Santhanam DR, Cho ER, Qu K, Jha S, Jha V, Suraweera W,  Wen R, Sinha SR, Gingras AC, Chakraborty P, Slutsky  AS, Jha P. COVID symptoms, seroprevalence, and mortality during the first wave of SARS-CoV-2 in Canada. medRxiv [Preprint]. 2021 Mar 5. doi: 10.1101/2021.03.04.21252540.

K Wilson and C Flood. Implementing digital passports for SARS-CoV-2 immunization in Canada. CMAJ. 2021 Mar 2:193(10). doi: 10.1503/cmaj.210244.

Rébillard RM, Charabati M, Grasmuck C, Filali-Mouhim A, Tastet O, Brassard N, Daigneault A, Bourbonnière L, Anand SP, Balthazard R, Beaudoin-Bussières G, Gasser R, Benlarbi M, Carmena Moratalla A, Carpentier Solorio Y, Boutin M, Farzam-Kia N, Descôteaux-Dinelle J, Fournier AP, Gowing EM, Laumaea A, Jamann H, Lahav B, Goyette G, Lemaître F, Mamane VH, Prévost J, Richard J, Thai K, Cailhier JF, Chomont N, Finzi A, Chassé M, Durand M, Arbour N, Kaufmann DE, Prat A, Larochelle C. Identification of SARS-CoV-2-specific immune alterations in acutely ill patients. J Clin Invest. 2021 Feb 26:145853. doi: 10.1172/JCI145853

Nazy I, Jevtic SD, Moore JC, Huynh A, Smith JW, Kelton JG, Arnold DM. Platelet-activating immune complexes identified in critically ill COVID-19 patients suspected of heparin-induced thrombocytopenia. J Thromb Haemost. 2021 Feb 27. doi: 10.1111/jth.15283.

Papenburg J , Cheng MP , Corsini R, Caya C, Mendoza E, Manguiat K, Lindsay LF , Wood H, Drebot MA, Dibernardo A , Zaharatos G , Bazin R, Gasser R, Benlarbi M , Gendron-Lepage G, Beaudoin-Bussières G, Prévost J, Finzi A, Ndao M, Yansouni C.  Evaluation of a commercial culture-free neutralization antibody detection kit for severe acute respiratory syndrome-related coronavirus-2 and comparison with an anti-RBD ELISA assay. Open Forum Infect Dis. 2021 Apr 30;8(6):ofab220. doi: 10.1093/ofid/ofab220

Anand SP, Prévost J, Richard J, Perreault J, Tremblay T, Drouin M, Fournier MJ, Lewin A, Bazin R, Finzi A. High-throughput detection of antibodies targeting the SARS-CoV-2 Spike in longitudinal convalescent plasma samples. Transfusion. 2021 Feb 18. doi: 10.1111/trf.16318.

Gasser R, Cloutier M, Prévost J, Fink C, Ducas É, Ding S, Dussault N, Landry P, Tremblay T, Laforce-Lavoie A, Lewin A, Beaudoin-Bussières G, Laumaea A, Medjahed H, Larochelle C, Richard J, Dekaban GA, Dikeakos JD, Bazin R, Finzi A. Major role of IgM in the neutralizing activity of convalescent plasma against SARS-CoV-2. Cell Rep. 2021 Feb 10:108790. doi: 10.1016/j.celrep.2021.108790.

Flood C, Thomas B, Wilson K. Mandatory vaccination for health care workers: an analysis of law and policy. CMAJ. 2021 Feb 8;193(6). doi.org/10.1503/cmaj.202755.

Saeed S, Drews SJ, Pambrun C, Yi QL, Osmond L, O’Brien SF. SARS‐CoV‐2 seroprevalence among blood donors after the first COVID‐19 wave in Canada. Transfusion. 2021 Feb 1. doi: 10.1111/trf.16296.

Bolotin S, Tran V, Osman S, Brown KA, Buchan SA, Joh E, Deeks SL, Allen VG. SARS-CoV-2 seroprevalence survey estimates are affected by anti-nucleocapsid antibody decline. J Infect Dis. 2021 Jan 5:jiaa796. doi: 10.1093/infdis/jiaa796.

Law JC, Koh WH, Budylowski P, Lin J, Yue F, Abe KT, Rathod B, Girard M, Li Z, Rini JM, Mubareka S, McGeer A, Chan AK, Gingras AC, Watts TH, A Ostrowski M. Systematic examination of antigen-specific recall T cell responses to SARS-CoV-2 versus influenza virus reveals a distinct inflammatory profile. J Immunol. 2021 Jan 1;206(1):37-50. doi: 10.4049/jimmunol.2001067.

Lu M, Uchil PD, Li W, Zheng D, Terry DS, Gorman J, Shi W, Zhang B, Zhou T, Ding S, Gasser R, Prévost J, Beaudoin-Bussières G, Anand SP, Laumaea A, Grover JR, Liu L, Ho DD, Mascola JR, Finzi A, Kwong PD, Blanchard SC, Mothes W. Real-time conformational dynamics of SARS-CoV-2 spikes on virus particles. Cell Host & Microbe. 2020 Dec 9;28(6):880-891. doi: 0.1016/j.chom.2020.11.001.

Ding S, Laumaea A, Benlarbi M, Beaudoin-Bussières G, Gasser R, Medjahed H, Pancera M, Stamatatos L, McGuire AT, Bazin R, Finzi A. Antibody binding to SARS-CoV-2 S glycoprotein correlates with but does not predict neutralization. Viruses. 2020 Oct 26; 12(11):1214. doi: 10.3390/v12111214.

Prévost J, Gasser R, Beaudoin-Bussières G, Richard J, Duerr R, Laumaea A, Anand SP, Goyette G, Benlarbi M, Ding S, Medjahed H, Lewin A, Perreault J, Tremblay T, Gendron-Lepage G, Gauthier N, Carrier M, Marcoux D, Piché A, Lavoie M, Benoit A, Loungnarath V, Brochu G, Haddad E, Stacey HD, Miller MS, Desforges M, Talbot PJ, Maule GTG, Côté M, Therrien C, Serhir B, Bazin R, Roger M, Finzi A. Cross-sectional evaluation of humoral responses against SARS-CoV-2 Spike. Cell Rep Med. 2020 Oct 20;1(7):100126. doi: 10.1016/j.xcrm.2020.100126.

Beaudoin-Bussières G, Laumaea A, Anand SP, Prévost J, Gasser R, Goyette G, Medjahed H, Perreault J, Tremblay T, Lewin A, Gokool L, Morrisseau C, Bégin P, Tremblay C, Martel-Laferrière V, Kaufmann D, Richard J, Bazin R, Finzi A. Decline of humoral responses against SARS-CoV-2 spike in convalescent individuals. mBio. 16 Oct 2020. doi: 10.1128/mBio.02590-20.

Anand SP, Chen Y, Prévost J, Gasser R, Beaudoin-Bussières G, Abrams CF, Pazgier M, Finzi A. Interaction of human ACE2 to membrane-bound SARS-CoV-1 and SARS-CoV-2 S glycoproteins. Viruses. 2020 Sep 29;12(10):1104. doi: 10.3390/v12101104.

Arora RK, Joseph A, Van Wyk J, Rocco S, Atmaja A, May E, Yan T, Bobrovitz N, Chevrier J, Cheng MP, Williamson T. SeroTracker: a global SARS-CoV-2 seroprevalence dashboard. Lancet Infect Dis. 2020 Aug. doi: 10.1016/S1473-3099(20)30631-9

Publications from Our Experts

Stephen B. Freedman and James D. Kellner. Protecting Canada’s children from the consequences of the fourth wave of the COVID-19 pandemic. CMAJ September 27, 2021 193 (38) E1500-E1502; DOI: https://www.cmaj.ca/content/193/38/E1500

Vinh DC, Abel L, Bastard P, Cheng MP, Condino-Neto A, Gregersen PK, Haerynck F, Cicalese MP, Hagin D, Soler-Palacín P, Planas AM. Harnessing Type I IFN Immunity Against SARS-CoV-2 with Early Administration of IFN-β. Journal of Clinical Immunology. 2021 Jun 8:1-8.

Yang J, D’Souza R, Kharrat A, Fell DB, Snelgrove JW, Murphy KE, Shah P.. COVID‐19 pandemic and population‐level pregnancy and neonatal outcomes: a living systematic review and meta‐analysisActa Obstet et Gynecol Scand 2021;100:1756–70. doi:10.1111/aogs.14206

Drouin O, Moore Hepburn C, Farrar DS, Baerg K, Chan K, Cyr C, Donner EJ, Embree JE, Farrell C, Forgie S, Giroux R, Kang KT, King M, Laffin M, Luu TM, Orkin J, Papenburg J, Pound CM, Price VE, Purewal R, Sadarangani M, Salvadori MI, Top KA, Viel-Thériault I, Kakkar F et Morris SK. Characteristics of children admitted to hospital with acute SARS-CoV-2 infection in Canada in 2020CMAJ September 27, 2021 193 (38) E1483-E1493; DOI: https://www.cmaj.ca/content/193/38/E1483

Skowronski DM, Setayeshgar S, Zou M, Prystajecky N, Tyson JR, Sbihi H, Fjell CD, Galanis E, Naus M, Patrick DM, El Adam S. Comparative single-dose mRNA and ChAdOx1 vaccine effectiveness against SARS-CoV-2, including early variants of concern: a test-negative design, British Columbia, CanadamedRxiv. 2021 Sept 22. doi : 10.1101/2021.09.20.21263875

Luong L, Beder M, Nisenbaum R, Orkin A, Wong J, Damba C, Emond R, Lena S, Wright V, Loutfy M, Bruce-Barrett C, Cheung W, Cheung YK, Williams V, Vanmeurs M, Boozary A, Manning H, Hester J, Hwang SW, 2021. Prevalence of SARS-CoV-2 infection among people experiencing homelessness in Toronto during the first wave of the COVID-19 pandemic. medRxiv, September 26, 2021. doi:10.1101/2021.09.21.21263713

Top KA, Bettinger JA, Kwong JC, Wilson SE, Hapuhennedige S. Enhancing Canada’s Vaccine Safety Surveillance for COVID-19 Vaccination Programs. CANvax. 2021 Sep 8. https://canvax.ca/brief/enhancing-canadas-vaccine-safety-surveillance-covid-19-vaccination-programs / Top KA, Bettinger JA, Kwong JC, Wilson SE, Hapuhennedige S. Renforcement de la surveillance de l’innocuité des vaccins dans les programmes de vaccination contre la COVID-19 au Canada. CANvax. 2021 Sep 8. https://canvax.ca/fr/brief/renforcement-de-la-surveillance-de-linnocuite-des-vaccins-dans-les-programmes-de-vaccination

Stone M, Grebe E, Sulaeman H, Di Germanio C, Dave H, Kelly K, Biggerstaff B, Crews BO, Tran N, Jerome KR, Denny TN, Hogema B, Destree M, Jones JM, Thornburg N, Simmons G, Krajden M, Kleinman S, Dumont LJ, Busch MP. Evaluation of commercially available high-throughput SARS-CoV-2 serological assays for serosurveillance and related applications. medRxiv doi: 10.1101/2021.09.04.21262414

Savitz DA, Bengtson AM, Hardy E, Fell DB. Pregnancy and the Risk of Severe COVID-19 Infection: Methodologic Challenges and Research Recommendations. BJOG. 18 Sep 2021. doi: 10.1111/1471-0528.16935.

Velásquez García HA, Wilton J, Smolina K, Chong M, Rasali D, Otterstatter M, Rose, C, Prystajecky, N, David, S, Galanis, E, McKee, G, Krajden M, Zafar Janjua, NZ. Mental health and substance use associated with hospitalization among people with laboratory confirmed diagnosis of COVID-19 in British Columbia: a population-based cohort study. medRxiv. 2021 Aug 28. doi: 10.1101/2021.08.26.21262697

Kaida A, Brotto LA,  Murray MCM,  Cote HCF,  Albert AY,  Nicholson V,  Gormley R,  Gordon S,  Booth A,  Smith LW,  Baaske A,  Galea LAM,  Sadarangani M, Ogilvie GS. Intention to receive a COVID-19 vaccine by HIV status among a population-based sample of women and gender diverse individuals in British Columbia, Canada. Aug 22, 2021: https://www.medrxiv.org/content/10.1101/2021.08.19.21262249v1 doi: https://doi.org/10.1101/2021.08.19.21262249

Bastard P, …, [Vinh DC] …, et al. Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths. Science immunol. 2021;6(62):eabl4340.

Fisman DN, Greer AL, Brankston G, Hillmer M, O’Brien SF, Drews SJ, Tuite AR. COVID-19 Case Age Distribution: Correction for Differential Testing by Age. Ann Intern Med. doi:10.7326/M20-7003

Sundaram M, Nasreen S, Calzavara A, He S, Chung H, Bronskill SE, Buchan SA, Tadrous M, Tanuseputro P, Wilson W, Wilson S, Kwong JC. Background rates of all-cause mortality, hospitalizations, and emergency department visits among nursing home residents in Ontario, Canada to inform COVID-19 vaccine safety assessments. Vaccine, 39 (2021) 5265-5270. Doi: https://doi.org/10.1016/j.vaccine.2021.07.060

Nault L, Marchitto L, Goyette G, Tremblay-Sher D, Fortin C, Martel-Laferrière V, Trottier B, Richard J, Durand M, Kaufmann D, Finzi A, Tremblay C. Covid-19 vaccine immunogenicity in people living with HIV-1. bioRxiv 2021.08.13.456258. doi : https://doi.org/10.1101/2021.08.13.456258

Gobeil PA, Pillet S, Boulay I, Charland N, Lorin A, Cheng M, Vinh D, Boutet P, Van Der Most R, Roman F, Perez MAC, D’Aoust MA, Landry N, Ward BJ. Durability and Cross-Reactivity of Immune Responses Induced by an AS03 Adjuvanted Plant-Based Recombinant Virus-Like Particle Vaccine for COVID-19. medRxiv. 2021 Jan 1. doi: 10.1101/2021.08.04.21261507

Hall VG, Ferreira VH, Ku T, Ierullo M, Majchrzak-Kita B, Chaparro C, Selzner N, Schiff J, McDonald M, Tomlinson G, Kulasingam V, Kumar D, Humar A. Randomized Trial of a Third Dose of mRNA-1273 Vaccine in Transplant Recipients. N Engl J Med, 2021 Aug 11. doi: 10.1056/NEJMc2111462.

Parotto M, Nainan MS, Munblit D, Elhazmi A, Ranzani O, Herridge M. Recovery after prolonged ICU treatment in patients with COVID-1. The Lancet Respiratory Medicine, Volume 9, Issue 8, 812 – 814 DOI: https://doi.org/10.1016/S2213-2600(21)00318-0

Groves H, Piché‐Renaud PP, Allen U. The significance and impact of SARS‐CoV‐2 variants of concern in pediatric solid organ transplantation: More unknowns than knownsPediatric Transplantation. 2021 Jun 16. DOI: 10.1111/petr.14071

Xia Y, Ma H, Moloney G, Velásquez García HA, Sirski M, Janjua NZ, Vickers D, Williamson T, Katz A, Yu K, Kustra R, Buckeridge DL, Brisson M, Baral SD, Mishra S, Maheu-Giroux M, 2021. Geographical concentration of COVID-19 cases by social determinants of health in 16 large metropolitan areas in Canada – a cross-sectional study. medRxiv 2021.07.23.21261039; doi:10.1101/2021.07.23.21261039

Lewin, A., Therrien, R., De Serres, G., Grégoire, Y., Perreault, J., Drouin, M., Fournier, M. J., Tremblay, T., Beaudoin, J., Beaudoin-Bussières, G., Prévost, J., Gendron-Lepage, G., Finzi, A., Bernier, F., Bazin, R., Germain, M., & Delage, G. (2021). SARS-CoV-2 seroprevalence among blood donors in Québec, and analysis of symptoms associated with seropositivity: a nested case-control study. Canadian journal of public health, Revue canadienne de santé publique, 112(4), 576–586. https://doi.org/10.17269/s41997-021-00531-6

Nourbakhsh S, Fazil A, Li M, Mangat CS, Peterson SW, Daigle J, Langner S, Shurgold J, D’Aoust P, Delatolla R, Mercier E, Pang X, Lee BE, Stuart R, Wijayasri S, Champredon D.  A Wastewater-based epidemic model for SARS-CoV-2 with application to three Canadian cities. medRxiv. July 25 2021. doi: https://doi.org/10.1101/2021.07.19.21260773

Bolotin S, Wilson S, Murti M. Achieving and sustaining herd immunity to SARS-CoV-2. CMAJ Jul 2021, 193 (28) E1089; DOI: 10.1503/cmaj.210892

Wilson K, Sher G., Philpott J. Preparing for the next pandemic by creating Canadian Immunization Services. Canadian Medical Association Journal 2021, 193, E1092–E1093. Doi:10.1503/cmaj.210670

Racey, C.S., Donken, R., Porter, I., Albert, A., Bettinger, J.A., Mark, J., Bonifacio, L., Dawar, M., Gagel, M., Kling, R., Mema, S., Mitchell, H., Roe, I., Ogilvie, G., Sadarangani, M., 2021. Intentions of public school teachers in British Columbia, Canada to receive a COVID-19 vaccine. Vaccine: X 8, 100106. doi: 10.1016/j.jvacx.2021.100106

Huynh A, Kelton JG, Arnold DM, Daka M, Nazy I. Antibody epitopes in vaccine-induced immune thrombotic thrombocytopenia. Nature (2021). https://doi.org/10.1038/s41586-021-03744-4

The CONCOR-1 Study GroupCONCOR-1 writing committee, Bégin P, Callum J, Jamula E, Cook R, Heddle NM, Tinmouth A, Zeller MP, Beaudoin-Bussières G, Amorim L, Bazin R, Loftsgard KC, Carl R, Chassé M, Cushing MM, Daneman N, Devine DV, Dumaresq J, Fergusson DA, Gabe C, Glesby MJ, Li N, Liu Y, McGeer A, Robitaille N, Sachais BS, Scales DC, Schwartz L, Shehata N, Turgeon AF, Wood H, Zarychanski R, Finzi A, Arnold DMfor The CONCOR-1 Study Group. Convalescent plasma for hospitalized patients with COVID-19 and the effect of plasma antibodies: a randomized controlled, open-label trial.

Abdulnoor M, Eshaghi A, Perusini SJ, Corbeil A, Cronin K, Fittipaldi N, Forbes JD, Guthrie JL, Kus JV, Majury A, Mazzulli T, Melano RG, Olsha R, Sullivan S, Tran V, Patel SN, Allen VG, Gubbay JB. Real-time RT-PCR allelic discrimination assay for detection of N501Y mutation in the spike protein of SARS-CoV-2 associated with variants of concern.

Sadarangani M, Marchant A, Kollmann TR. Immunological mechanisms of vaccine-induced protection against COVID-19 in humans. Nat Rev Immunol. 2021 Jul 1. doi: 10.1038/s41577-021-00578-z.

Zhang Y, Malekjahani A, Udugama BN, Kadhiresan P, Chen H, Osborne M, Franz M, Kucera M, Plenderleith S, Yip L, Bader GD, Tran V, Gubbay JB, McGeer A, Mubareka S, Chan WCW. Surveilling and tracking COVID-19 patients using a portable quantum dot smartphone device. Nano Lett. 2021 Jun 23;21(12):5209-5216. doi: 10.1021/acs.nanolett.1c01280.

Bennet SMP, Kaufmann M, Takami K, Sjaarda C, Douchant K, Moslinger E, Wong H, Reed DE, Ellis AK, Vanner S, Colautti RI, Sheth PM. Small-molecule metabolome identifies potential therapeutic targets against COVID-19.

Greenhawt M, Abrams EM, Shaker M, Chu DK, Kahn D, Akin C, Alqurashi W, Arkwright P, Baldwin JL, Ben-Shoshan M, Bernstein J, Bingeman T, Blumchen K, Byrne A, Bognanni A, Campbell D, Campbell R, Chagla Z, Chan ES, Chan J, Comberiatti P, Dribin TE, Ellis AK, Fleischer DM, Fox A, Frischmeyer-Guerrerio PA, Gagnon R, Grayson MH, Horner CC, Hourihane J, Katelaris CH, Kim H, Kelso JM, Lang D, Ledford D, Levin M, Lieberman J, Loh R, Mack D, Mazer B, Mosnaim G, Munblit D, Mustafa SS, Nanda A, Oppenheimer J, Perrett KP, Ramsey A, Rank M, Robertson K, Shiek J, Spergel JM, Stukus D, Tang MLK, Tracy JM, Turner PJ, Whalen-Browne A, Wallace D, Wang J, Wasserman S, Witty JK, Worm M, Vander Leek TK, Golden DBK. The risk of allergic reaction to SARS-CoV-2 vaccines and recommended evaluation and management: A systematic review, meta-analysis, GRADE assessment, and international consensus approach. J. Allergy Clin. Immunol. 2021 Jun 18. doi: 10.1016/j.jaip.2021.06.006.

Griffin BD, Chan M, Tailor N, Mendoza EJ, Leung A, Warner BM, Duggan AT, Moffat E, He S, Garnett J, Tran KN, Banadyga L, Albietz A, Tierney K, Audet J, Bello A, Vendramelli R, Boese AS, Fernando L, Lindsay LR, Jardine CM, Wood H, Poliquin G, Strong JE, Drebot M, Safronetz D, Embury-Hyat C, Kobasa D. SARS-CoV-2 infection and transmission in the North American deer mouse. Nat Commun. 2021 Jun 14;12:3612. doi: 10.1038/s41467-021-23848-9.

Brotto LA, Chankasingh K, Baaske A, Albert A, Booth A, Kaida A, Smith LW, Racey S, Gottschlich A, Murray MCM, Sadarangani M, Ogilvie GS, Galea L. The influence of sex, gender, age, and ethnicity on psychosocial factors and substance use throughout phases of the COVID-19 pandemic. medRxiv. 2021 Jun 10. doi: 10.1101/2021.06.08.21258572.

Skowronski DM, Setayeshgar S, Zou M, Prystajecky N, Tyson JR, Galanis E, Naus M, Patrick DM, Sbihi H, El Adam S, Henry B, Hoang LMN, Sadarangani M, Jassem AN, Krajden M. Single-dose mRNA vaccine effectiveness against SARS-CoV-2, including P. 1 and B. 1.1. 7 variants: a test-negative design in adults 70 years and older in British Columbia, Canada. medRxiv. 2021 Jun 9. doi: 10.1101/2021.06.07.21258332.

Bourguignon A, Arnold DM, Warkentin TE, Smith JW, Pannu T, Shrum JM, Al Maqrashi ZAA, Shroff A, Lessard M-C, Blais N, Kelton JG, Nazy I. Adjunct immune globulin for vaccine-induced thrombotic thrombocytopenia. N Engl J Med. 2021 Jun 9. doi: 10.1056/NEJMoa2107051.

Vinh DC, Abel L, Bastard P, Cheng MP, Condino-Neto A, Gregersen PK, Haerynck F, Cicalese MP, Hagin D, Soler-Palacín P, Planas AM, Pujol A, Notarangelo LD, Zhang Q, Su HC, Casanova JL, Meyts I; COVID Human Genetic Effort. Harnessing type I IFN immunity against SARS-CoV-2 with early administration of IFN-β. J Clin Immunol. 2021 Jun 8:1–18. doi: 10.1007/s10875-021-01068-6.

Verma AA, Hora T, Jung HY, Fralick M, Malecki SL, Lapointe-Shaw L, Weinerman A, Tang T, Kwan JL, Liu JJ, Rawal S, Chan TCY, Cheung AM, Rosella LC, Ghassemi M, Herridge M, Mamdani M, Razak F. Caractéristiques et issues des hospitalisations pour les cas de COVID-19 et d’influenza dans la région de Toronto.

Bullard J, Funk D, Dust K, Garnett L, Tran K, Bello A, Strong JE, Lee SJ, Waruk J, Hedley A, Alexander D, Caeseele PV, Loeppky C, Poliquin G. Comparaison de l’infectivité du coronavirus du syndrome respiratoire aigu sévère 2 chez les enfants et les adultes.

Liu M, Arora RK, Krajden M. Tests de détection rapides d’antigènes pour le SRAS-CoV-2.

Reyes Domingo F, Waddell LA, Cheung AM, Cooper CL, Belcourt VJ, Zuckermann AME, Corrin T, Ahmad R, Boland L, Laprise C, Idzerda L, Khan A, Jaramillo Garcia A. Prevalence of long-term effects in individuals diagnosed with COVID-19: a living systematic review. medRxiv. 2021 Jun 6. doi:10.1101/2021.06.03.21258317.

Tauzin A, Nayrac M, Benlarbi M, Gong SY, Gasser R, Beaudoin-Bussières G, Brassard N, Laumaea A, Vézina D, Prévost J, Anand SP, Bourassa C, Gendron-Lepage G, Medjahed H, Goyette G, Niessl J, Tastet O, Gokool L, Morrisseau C, Arlotto P, Stamatatos L, McGuire AT, Larochelle C, Uchil P, Lu M, Mothes W, De Serres G, Moreira S, Roger M, Richard J, Martel-Laferrière V, Duerr R, Tremblay C, Kaufmann DE, Finzi A. A single dose of the SARS-CoV-2 vaccine BNT162b2 elicits Fc-mediated antibody effector functions and T-cell responses. Cell Host and Microbe. 2021 Jun 4. doi: 10.1016/j.chom.2021.06.001.

Betti M, Bragazzi N, Heffernan J, Kong J, Raad A. Could a new COVID-19 mutant strain undermine vaccination efforts? A mathematical modelling approach for estimating the spread of B.1.1.7 using Ontario, Canada, as a case study. Vaccines. 2021 Jun 3; 9(6):592. doi: 10.3390/vaccines9060592.

Heckman GA, Kay K, Morrison A, Grabowski DC, Hirdes JP, Mor V, Shaw G, Benjamin S, Boscart VM, Costa AP, Declercq A, Geffen L, Sang Lum TY, Moser A, Onder G, Van Hout H. Proceedings from an international virtual townhall: Reflecting on the COVID-19 pandemic: themes from long-term care. J Am Med Dir Assoc. 2021 Jun 1. doi: 10.1016/j.jamda.2021.03.029.

Goupil R, Benlarbi M, Beaubien-Souligny W, Nadeau-Fredette A-C, Chatterjee D, Goyette G, Gunaratnam L, Lamarche C, Tom A, Finzi A, Suri RS. Short-term antibody response afer 1 dose of BNT162b2 vaccine in patients receiving hemodialysis. CMAJ. 2021 May 31. doi: 10.1503/cmaj.210673.

Ogilvie GS, Gordon S, Smith LW, Albert A, Racey CS, Booth A, Gottschlich A, Goldfarb D, Murray MCM, Galea LAM, Kaida A, Brotto LA, Sadarangani M. Intention to receive a COVID-19 vaccine: results from a population-based survey in Canada. BMC Public Health. 2021 May 29;21(1):1017. doi: 10.1186/s12889-021-11098-9.

Wong ST, Romney M, Matic N, Haase K, Ranger M, Dhari R, Affleck F, Tan E, Ndateba I, Tobias E, Saewyc E, Schwandt M, Sin D. Feasibility and utility of rapid antigen testing for COVID-19 in a university residence: a cross sectional study. medRxiv. 2021 May 26. doi: 10.1101/2021.05.24.21257732.

Verma AA, Pai M, Saha S, Bean S, Fralick M, Gibson JL, Greenberg RA, Kwan JL, Lapointe-Shaw L, Tang T, Morris AM, Razak F. Managing drug shortages during a pandemic: tocilizumab and COVID-19. CMAJ. 2021 May 25;193(21):E771-E776. doi: 10.1503/cmaj.210531.

Yau K, Abe KT, Naimark D, Oliver MJ, Perl J, Leis JA, Bolotin S, Tran V, Mullin S, Shadowitz E, Garnham-Takaoka J, de Launay KQ, Takaoka A, Straus SE, McGeer AJ, Chan CT, Colwill K, Gingras A-C, Hladunewich MA. The humoral response to the BNT162b2 vaccine in hemodialysis patients.

Vogel TP, Top KA, Karatzios C, Hilmers DC, Tapia LI, Moceri P, Giovannini-Chami L, Wood N, Chandler RE, Klein NP, Schlaudecker EP, Poli MC, Muscal E, Munoz FM. Multisystem inflammatory syndrome in children and adults (MIS-C/A): Case definition & guidelines for data collection, analysis, and presentation of immunization safety data. Vaccine. 2021 May 21;39(22):3037-3049. doi: 10.1016/j.vaccine.2021.01.054.

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