The COVID-19 Immunity Task Force’s mandate
On April 23, 2020, the Government of Canada launched the COVID-19 Immunity Task Force (CITF). The Task Force’s mandate is to catalyze, support, fund and harmonize knowledge on SARS-CoV-2 immunity for federal, provincial, and territorial decision-makers in their efforts to protect Canadians and minimize the impact of the COVID-19 pandemic.
Priority Areas of Research
Immune Science
Advancing our understanding of immunity: Is immunity a given once someone has had COVID-19? How long does it last? Are there factors that make immunity wane faster?
Seroprevalence Studies
Collecting serologic data: How many Canadians have SARS-CoV-2 antibodies, suggesting they’ve had COVID-19? Are some populations more likely to get SARS-CoV-2 and how could we better protect them?
Immune Testing
Fine-tuning methods for accurate serologic testing: Which tests can detect the new variants? Are there antibody tests that can be developed giving us results in minutes?
Vaccine Surveillance
Supporting research partners from across Canada in a new collaboration that will study vaccine effectiveness and safety in the population at large and in high-priority groups.
Boosters
Understanding when and if the general population and sub-groups such as long-term care residents, racialized communities or Indigenous Peoples need booster shots.
Pediatric Vaccination
Researching the safety, effectiveness and immunogenicity of vaccines in children under 12 to help inform the roll out of vaccines.
Immunity Modelling
Modelling trends in the overall immunity across Canada arising from infection and vaccination.
CITF Monthly Review
January 2023 issue
In this month’s issue, we’d like to highlight:
- Spotlights on some of the latest CITF-funded research, including efforts to develop new COVID-19 vaccines, on page 4.
- An experts review piece on hybrid immunity, on pages 14-15.
- A summary of our seminar on the social determinants of health, on pages 12-13.
- New seroprevalence data on the most recent immunity rates across Canada, on pages 2-3.
CITF-funded Research Results
Preferences for COVID-19 vaccination in people with chronic immune-mediated inflammatory diseases
A CITF-funded study published in The Journal of Rheumatology highlighted that people with chronic immune-mediated inflammatory diseases (IMIDs) perceived the benefits of COVID-19 vaccination as outweighing their concerns over rare, though serious side effects and potential disease flare.
Vaccine effectiveness in people with chronic kidney disease can be reliably estimated using various study designs
A CITF-funded study conducted by Dr. Matthew Oliver (University of Toronto) and his team revealed that estimates of vaccine effectiveness (VE) in individuals diagnosed with chronic kidney disease are consistent across three common study designs: test-negative, pseudo-test-negative, and cohort studies.
Antibody responses against the BQ.1.1 subvariant elicited following SARS-CoV-2 mRNA vaccination and breakthrough infection
A partially CITF-funded, study, published in Vaccines, demonstrated that hybrid immunity, generated by vaccination and recent infection, induces higher humoral responses than vaccination alone against ancestral and Omicron variant BA.5 subvariant BQ.1.1 SARS-CoV-2 strains, regardless of which mRNA vaccine is administered.
Latest News
SeroTracker expands its SARS-CoV-2 serosurveillance hub
CITF-funded SeroTracker has added to its knowledge hub that tracks findings from SARS-CoV-2 serosurveillance efforts worldwide and in Canada. Peruse the maps and graphs and see how many people in this country (by province & territory as well) and around the world are estimated to have been infected with or vaccinated against this coronavirus to date (based on published research).
Explore SeroTracker
What is serosurveillance and why is it important?
Serosurveillance is a common way of seeing how many people have been previously infected with a certain infectious agent, in this case SARS-CoV-2, the virus causing COVID-19. Blood samples from hundreds of thousands of Canadians are currently being tested to check levels of antibodies, which suggest a past infection. Serosurveillance can also help determine priority groups for vaccination and will be used to monitor the effectiveness of vaccines.
What does “vaccine surveillance” mean?
Vaccine surveillance includes studies of vaccine effectiveness (how good vaccines are at preventing severe disease, new infections, and transmission) and safety (identifying and quantifying the vaccine adverse effects). Although vaccines go through numerous trials before being approved for use, it is crucial to monitor their effectiveness and safety within a broader population and with various population groups (children, pregnant women, elderly, etc.).
See all FAQs
What is serosurveillance and why is it important?
Serosurveillance is a common way of seeing how many people have been previously infected with a certain infectious agent, in this case SARS-CoV-2, the virus causing COVID-19. Blood samples from hundreds of thousands of Canadians are currently being tested to check levels of antibodies, which suggest a past infection. Serosurveillance can also help determine priority groups for vaccination and will be used to monitor the effectiveness of vaccines.
What does “vaccine surveillance” mean?
Vaccine surveillance includes studies of vaccine effectiveness (how good vaccines are at preventing severe disease, new infections, and transmission) and safety (identifying and quantifying the vaccine adverse effects). Although vaccines go through numerous trials before being approved for use, it is crucial to monitor their effectiveness and safety within a broader population and with various population groups (children, pregnant women, elderly, etc.).
See all FAQs
