The research we catalyze and fund in this category includes ongoing safety monitoring to ensure we know immediately if ever an issue were to arise. Our funded research also looks at a variety of questions such as: What are the effectiveness and immunogenicity of SARS-CoV-2 vaccination in children (be they healthy, immunocompromised, have cardiovascular complications, etc.)? What is the effect of SARS-CoV-2 vaccination on children who have already had Multisystem inflammatory Syndrome in children (MIS-C) or long COVID symptoms? When will children need boosters, if at all? What is the durability of vaccine-induced immune responses (humoral, cellular, absolute antibody level, neutralizing antibodies, cellular responses, recall responses) in children?