Immunity Task Force Members and Secretariat in the World Literature

Law, J.C., Koh, W.H., Budylowski, P., Lin, J., Yue, F., Abe, K.T., Rathod, B., Girard, M., Li, Z., Rini, J.M., Mubareka, S., McGeer, A., Chan, A.K., Gingras, A., Watts, T.H., Ostrowski, M.A.. (2020) Systematic Examination of Antigen-Specific Recall T Cell Responses to SARS-CoV-2 Versus Influenza Virus Reveals a Distinct Inflammatory Profile. J Immunol, DOI: 10.4049/jimmunol.2001067.

Ismail, S. J., Zhao, L., Tunis, M. C., Deeks, S. L., Quach, C. (2020). Key Populations for Early COVID-19 Immunization: Preliminary Guidance for Policy. CMAJ, 192(48), E1620-E1632.

Cheng, M.P., Yansouni, C.P., Basta, N.E., Desjardins, M., Kanjilal, S., Paquette, K., Caya, C., Semret, M., Quach, C., Libman, M., Mazzola, L., Sacks, J.A., Dittrich, S., Papenburg, J. (2020) Serodiagnostics for Severe Acute Respiratory Syndrome-Related Coronavirus 2. Ann Intern Med, DOI: 10.7326/M20-2854.

Arora RK, Joseph A, Van Wyk J, Rocco S, Atmaja A, May E, Yan T, Bobrovitz N, Chevrier J, Cheng MP, Williamson T. (2020) SeroTracker: a Global SARS-CoV-2 Seroprevalence Dashboard. Lancet Infect Dis, DOI: 10.1016/S1473-3099(20)30631-9

Beaudoin-Bussières, G., Laumaea, A., Anand, S.P., Prévost, J., Gasser, R., Goyette, G., Medjahed, H., Perreault, J., Tremblay, T., Lewin, A., Gokool, L., Morrisseau, C., Bégin, P., Tremblay, C., Martel-Laferrière, V., Kaufmann, D., Richard, J., Bazin, R., Finzi, A.. (2020) Decline of Humoral Responses against SARS-CoV-2 Spike in Convalescent Individuals. mBio, September/October 2020 Volume 11 Issue 5.

Van Caeseele, P., Bailey, D., Forgie, S.E., Dingle, T.C., Krajden, M. (2020). SARS-CoV-2 (COVID-19) serology: implications for clinical practice, laboratory medicine and public health. CMAJ, Aug 2020, 192 (34) E973-E979; DOI: 10.1503/cmaj.201588

Anderson, G., Frank, J. W., Naylor, C. D., Wodchis, W., & Feng, P. (2020). Using socioeconomics to counter health disparities arising from the covid-19 pandemic. BMJ, m2149. https://doi.org/10.1136/bmj.m2149

Cheng, M. P., Papenburg, J., Desjardins, M., Kanjilal, S., Quach, C., Libman, M., Dittrich, S., & Yansouni, C. P. (2020). Diagnostic Testing for Severe Acute Respiratory Syndrome–Related Coronavirus 2. Annals of Internal Medicine, 172(11), 726–734. https://doi.org/10.7326/m20-1301


TASK FORCE RESEARCH results

These are estimates of seroprevalence from Canadian Blood Services for the months of October and November 2020. The table below presents the estimated seroprevalence rates for Canada and the provinces served by CBS for the periods May-July, October, and November 2020. In Quebec, the serosurvey by Héma-Québec sampled once in 2020 during the first wave.

Table 1: Rate of antibody detection in Blood Donors in Canada

 Values % (95% confidence Interval)Values % (95% confidence Interval)Values % (95% confidence Interval)
DatesMay-JulyOctoberNovember
Canada0.70% (0.63-0.77)0.88% (0.73-1.04)1.51% (1.31-1.71)
British Columbia0.56% (0.41-0.70)0.86% (0.50-1.23)1.51% (1.04-1.97)
Alberta0.48% (0.33-0.62)0.76% (0.38-1.14)1.79% (1.24-2.34)
Saskatchewan0.53% (0.23-0.83)0.17% (0.00-0.59)4.17% (2.57-5.77)
Manitoba0.59% (0.30-0.88)2.96% (1.70-4.23)8.56% (6.51-10.62)
Ontario0.88% (0.78-0.99)0.87% (0.65-1.08)0.77% (0.56-0.97)
Quebec*1.06% (0.82-1.30)  
New Brunswick0.23% (0.00-0.49)0.17% (0.00-0.66)0.49% (0.00-1.20)
Nova Scotia0.69% (0.33-1.05)0.98% (0.11-1.85)0.19% (0.00-0.65)
Prince Edward Island0.04% (0.00-0.42)0%0%
Newfoundland0.44% (0.04-0.84)0.06% (0.00-0.52)0.95% (0.00-2.09)
Link to CBS report for May-July 2020Link to CBS report for October 2020Link to CBS report for November 2020

Task Force research funded to date

Primary Investigator/Researcher
Last nameFirst nameInstitutionProject Title
SadaranganiManishUniversity of British ColumbiaSPRING Study: SARS-CoV-2 seroprevalence in children and young adults in British Columbia
Statistics CanadaThe Canadian COVID-19 Antibody and Health Survey
AwadallaPhilipCanadian Partnership for Tomorrow’s Health (CanPath)National study looking at seroprevalence of COVID-19 antibodies among high-risk populations
ZinzserKateUniversité de Montréal and Centre for Public Health ResearchEnCORE Study: How many children and teens in Montreal have been infected with SARS-CoV-2
RainaParminderCanadian Longitudinal Study on Aging (CLSA)Canadian Longitudinal Study on Aging (CLSA): Platform for studying the epidemiology of the COVID-19 pandemic in aging populations (CLSA-COVID-19 Study)
MoneyDeborahUniversity of British ColumbiaCanadian Population Serological Survey Utilizing Antenatal Serum Samples
AwadallaPhilip Ontario Institute for Cancer ResearchSurveilling Prospective Population cOhorts for COVID19 pRevalence and ouTcomes in Canada (SUPPORT-Canada)
AzadMeghan University of ManitobaRapid research in the CHILD Cohort to inform Canada’s response to the COVID-19 pandemic: investigating the prevalence and predictors of SARS-CoV-2 infection, and the health and psychosocial impact of the COVID-19 pandemic on Canadian families
CherryNicola University of AlbertaThe impact of COVID-19 on the health of physicians, nurses and other healthcare workers: an interprovincial cohort study
CheungAngela University Health Network (Toronto)Canadian COVID-19 Prospective Cohort Study (CanCOV)
DrabovichAndrei University of AlbertaRational design and standardization of serology diagnostics using immunoaffinity-targeted proteomics assays
GraceDaniel University of TorontoEngage-COVID-19: A mixed methods study of biomedical, behavioural, and psychosocial aspects of the COVID-19 pandemic among gay, bisexual, and other men who have sex with men in Canada
GrantMichael Memorial Universty of NewfoundlandCharacterization of Cellular and Humoral Immunity Against SARS-CoV-2
HwangStephen Unity Health TorontoThe COVENANT Study: COVID-19 Cohort Study of People Experiencing Homelessness in Toronto
JarviKeith Sinai Health System (Toronto)Development of high throughput, inexpensive and scalable testing to detect SARS-CoV-2 antibodies using home blood collection kits and a fully automated ELISA antibody assay
KaufmannDaniel Centre hospitalier de l’Universite de Montreal (CHUM)Early immune predictors of sustained SARS-CoV-2 antibody responses after COVID-19 disease
LachowskyNathan University of VictoriaThe COVID-19 Pandemic Among Sexual and Gender Marginalized Populations in Canada: Physical Distancing Impacts, SARS-CoV-2 Seroprevalence, and Health and Wellness Needs
LangloisMarc-André University of OttawaAnalysis of Antibody Neutralization Efficiency and Cellular Immunity in SARS-CoV-2-Positive Individuals Identified in At-Risk Individuals
LittleDustin Ryerson UniversityA low-cost, portable, and decentralized microfluidic device for detecting SARS-CoV-2 neutralizing antibodies
MadathilSreenath Arekunnath McGill UniversityCOVID-19 incidence rates among Canadian dentists as they return to work: a cohort study
MaguireJonathon Unity Health TorontoTARGet Kids! COVID-19 Study of Children and Families: Safe Return to School, Work, and Play
McGeerAlisonSinai Health System (Toronto)Are healthcare workers at higher risk of COVID-19 than other working adults?
NazyIshac McMaster University Long-term protective immunity against SARS-CoV-2 virus in COVID-19 patients
O’ConnorDeborah Sinai Health System (Toronto) / University of TorontoCan COVID-19 and maternal antibodies to SARS-CoV-2 be transmitted through human milk? Implications for breastfeeding and human milk banking
Quach-ThanhCaroline Centre hospitalier universitaire Sainte-JustineREinfection in COVid-19 Estimation of Risk (RECOVER)
TroyerRyan University of Western OntarioSimple assay to assess antibody-dependent enhancement of SARS-CoV-2
WattsTania University of TorontoTowards a comprehensive understanding of adaptive immunity to SARS-CoV-2
WilsonKumanan Bruyère Research InstituteImmunity Passports for COVID-19: Scientific, Ethical, Policy and Design Implications
  Canadian Blood ServicesCollaborative nine-province SARS-CoV-2 seroprevalence study based on 37,373 blood samples from blood donor centres across Canada (except Quebec and the Territories)