ICD-10 diagnostic codes could identify most lab-confirmed SARS-CoV-2 infections in hospital-admitted patients but were less sensitive for discharged patients
A CITF-supported study, published in Scientific Reports, aimed to assess the operating characteristics of the International Classification of Diseases Revision 10 (ICD-10) code introduced by the World Health Organization in 2020.
Maternity and infant outcomes have improved with the rise of less severe SARS-CoV-2 strains and availability of multiple COVID-19 vaccine doses
The 6th report (to December 2022) from the CITF-funded Canadian Surveillance of COVID-19 in Pregnancy (CANCOVID-Preg) project showed a decline since December 2021 in intensive care unit admissions and hospitalizations for pregnant people diagnosed with COVID-19.
Seropositivity rates among pregnant people were about four times higher than documented PCR-positive rates
A CITF-funded report published in March 2022 by the Canadian COVID-19 Population Serological Survey Utilizing Antenatal Serum Samples (Antenatal Serostudies) project leveraged existing blood samples collected through routine prenatal screening to assess immunity levels in the general population through the lens of the pregnant population.
CANCOVID-Preg: key aims and protocols
A CITF-funded group, Canadian Surveillance of COVID-19 in Pregnancy (CANCOVID-Preg), published a research letter in the Journal of Obstetrics and Gynaecology Canada in 2021, summarizing its aims and protocols focused on the maternal-newborn population as a pan-Canadian national response to COVID-19.
Clinical risk factors for adverse outcomes among those who had COVID-19 during pregnancy or postpartum
A study funded in part by CITF, published in the American Journal of Obstetrics and Gynecology, found that comorbidities, nutritional status, and older age were associated with severe COVID-19-related outcomes, adverse pregnancy outcomes, and fetal/neonatal morbidity and mortality.
There is practical utility in using SPR sensors for clinical studies
A CITF-funded study, published as a preprint and not yet peer-reviewed, found that a surface plasmon resonance (SPR) sensor, which can provide quantitative biomolecular information and can be used in point-of-care settings, is a viable alternative for monitoring SARS-CoV-2 humoral immune responses.
Individuals living with HIV receiving antiretroviral therapy mount strong T cell responses to COVID-19 vaccines
A CITF-funded study, published as a pre-print and not yet peer-reviewed, found that people living with HIV (PLWH) receiving antiretroviral therapy mount strong T cell responses to COVID-19 vaccines that are enhanced by booster doses or breakthrough infection.
The methodology of the CHILD sub-study to examine the effect of SARS-CoV-2 infection on children
The study design and cohort profile of a CITF-funded study have been published in Epidemiology and Health. The research aimed to examine the prevalence and predictors of SARS-CoV-2 infection and transmission, as well as the predictors of the health and psychosocial impact of the COVID-19 pandemic, among Canadian children and their families.
Blanket SARS-CoV-2 screening among those admitted to hospital for non-COVID-19 conditions not worthwhile back in 2020
A CITF-funded study, published in BMJ Open, found that universal COVID-19 screening among adults admitted to hospital over two waves in 2020 with a diagnosis unrelated to COVID-19 had a low diagnostic yield, meaning universal screening, at the time, would not have been justifiable as a blanket policy.