This commentary From Dr. David Savitz and CITF-funded researcher Dr. Deshayne Fell outlines specific methods that should be implemented in research to more effectively assess the risk of severe COVID-19 among pregnant individuals. The article touches upon methodological challenges including increased surveillance, enhanced clinical responses to illness, and confounding. It also gives an overview of the current evidence on COVID-19 and pregnancy while offering study design and analysis strategies to strengthen causal inference.
Savitz DA, Bengtson AM, Hardy E, Fell DB. Pregnancy and the Risk of Severe COVID-19 Infection: Methodologic Challenges and Research Recommendations. BJOG. 18 Sep 2021. doi: 10.1111/1471-0528.16935.