How can serosurveys be used in the vaccine era?

In this preprint, not yet peer reviewed, led by SeroTracker, CITF-funded researchers and CITF Secretariat employees, the authors present an approach to help interpret serosurvey results and distinguish between infection-acquired and vaccine-induced immunity. Making the distinction between how infection and vaccine induced  immunity can help guide public health officials worldwide in their strategy for [...]

2022-01-10T10:39:40-05:00January 10, 2022|Other|

Making life easier for researchers doing systematic reviews of seroprevalence studies

Making life easier for researchers doing systematic reviews of seroprevalence studies Researchers at CITF-funded Serotracker present a new automated tool designed for risk of bias assessment (ROB). Because ROB can be a time consuming and subjective task when performing a systematic review, in this preprint, not yet peer reviewed, the authors offer a set [...]

2021-11-30T12:53:47-05:00November 30, 2021|Other|

Explaining the limited utility of convalescent plasma from the first phase of the COVID-19 pandemic in treating those newly infected

The continued persistence of SARS-CoV-2 infections in predominantly unvaccinated individuals has meant a continued need for therapeutics to treat those hospitalized with COVID-19. Convalescent plasma containing SARS-CoV-2 neutralizing antibodies from recovered individuals is one therapy option but has been controversial. A new publication in Transfusion by CITF-funded researchers Drs. Steven Drews and Sheila O’Brien [...]

2021-11-02T09:24:08-04:00October 29, 2021|Other|

Plant-produced proteins for SARS-COV-2 could expand vaccine-delivery options

It is increasingly clear that vaccines are among the primary solutions to the COVID-19 pandemic. However, cost-effective and large-scale production is key for ensuring vaccination all over the world, specifically in lower-middle income countries. In this pre-print, not yet peer-reviewed, study that was partly funded by the CITF and led by Dr. Marc-André Langlois [...]

2021-11-02T11:05:14-04:00October 29, 2021|Other|

A comprehensive review of international vaccine certificate programs for COVID-19

Vaccine certificates or "passports" are becoming more commonplace, with access to restaurants, event venues, and even workplaces increasingly dependent on proof of vaccination against COVID-19. To better understand how different jurisdictions are implementing digital vaccine certificates, researchers from the Ottawa Hospital Research Institute, including CITF-funded researcher Dr. Kumanan Wilson, performed a review of available [...]

2021-10-19T20:53:14-04:00October 19, 2021|Other|

Careful vigilance of population immunity, booster vaccines, masks, and social distancing required to fend off a new COVID wave

A study out in preprint in August (and therefore not yet peer-reviewed) led by CITF Scientific Advisor Dr. Jane Heffernan and which included CITF Scientific Lead, Data Management & Analysis, Dr. David Buckeridge, modelled immunity to COVID-19 across Canada. The scientists used a mathematical model to determine the distribution of immunity in the Canadian [...]

2021-09-07T14:50:22-04:00September 7, 2021|Other|

Cutting-edge technologies can be used to anticipate functional and clinical impact of new variants of SARS-CoV-2

In a recent review in Clinical Proteomics, Dr. Andrei Drabovich and his team from University of Alberta provide insights on the use of cutting-edge technologies to empower basic and clinical research on COVID-19. Most importantly, they describe how these methodologies can be used to detect existing and novel viral variants. Mass spectrometry is a [...]

2021-08-23T21:02:19-04:00August 24, 2021|Other|

Tracking and mapping new mutations of SARS-CoV-2 across the globe

Dr. Marc-André Langlois and his team at the University of Ottawa analyzed mutations in SARS-CoV-2 from December 2019 to December 2020, including the impact on virus biology, therapeutics and vaccine effectiveness. This study was supported by the Canadian Institutes of Health Research (CIHR) and the COVID-19 Immunity Task Force (CITF). In this pre-print, the [...]

2021-03-15T10:59:02-04:00March 15, 2021|Other|

Passport to normal: CITF researcher Kumanan Wilson comments on the future of immunity passports

With vaccine coverage on the horizon, many people are starting to think about how to document immunization. In this article, CITF-funded researcher Dr. Kumanan Wilson from the University of Ottawa and the Bruyère Research Institute and colleague Colleen Flood from the University of Ottawa, discuss how SARS-CoV-2 immunization passports could work, the infrastructure required [...]

2021-03-08T14:39:35-05:00March 3, 2021|Other|
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