Publications de recherche

Publications de recherche2021-11-26T14:50:02-05:00

Publications issues de la recherche financée par le GTIC

McKinnon B, Quach C, Dubé E, Nguyen CT, Zinszer K. Social inequalities in COVID-19 vaccine acceptance and uptake for children and adolescents in Montreal, Canada: a cross-sectional studyVaccinedoi: https://doi.org/10.1016/j.vaccine.2021.10.077

Kronfi N, Dussault C, Maheu-Giroux M, Halavrezos A, Chalifoux S, and Sherman J, Park, H, Del Balso L, Cheng MP, Poulin S, Cox J. Seroprevalence and Risk Factors for SARS-CoV-2 Among Incarcerated Adult Men in Quebec, Canada (2021): A Cross-Sectional Study. Pre-print The Lancet, November 9 2021 Doi: http://dx.doi.org/10.2139/ssrn.3959665

Breznik JA, Zhang A, Huynh A, Miller MS, Nazy I, Bowdish DME, Costa AP, Antibody Responses 3-5 Months Post-Vaccination with mRNA-1273 or BNT163b2 in Nursing Home Residents, JAMDA, DOI: https://doi.org/10.1016/j.jamda.2021.10.001

MacDonald C, Demers PA, Grunau B, Goldfarb D, O’Neill D, Armour R, Kirkham TL; Mental Health and Life Satisfaction Among Canadian Paramedics during the COVID-19 Pandemic.

Madathil S, Siqueira WL, Marin LM, Sanaulla FB, Faraj N, Quiñonez CR, et al. The incidence of COVID-19 among dentists practicing in the community in Canada: A prospective cohort study over a six-month period. The Journal of the American Dental Association. J Am Dent Assoc; 2021; DOI: https://doi.org/10.1016/j.adaj.2021.10.006

Fu Z, Rais, Y, Drabovich AP. Immunoprecipitation-targeted proteomics assays facilitate rational development of SARS-CoV-2 serological diagnostics. medRxiv. 25 Oct 2021. doi: 10.1101/2021.10.25.21265408v1

Drews SJ, Abe KT, Hu Q, Samson R, Gingras AC, Colwill K, Rathod B, Wang J, Fazel‐Zarandi M, Yi QL, Robinson A. Resistance of SARS‐CoV‐2 Beta and Gamma variants to plasma collected from Canadian blood donors during the Spring of 2020Transfusion. 2021 Oct 18. doi: 10.1111/trf.16713

Colwill K, Galipeau Y, Stuible M, Gervais C, Arnold C, Rathod B, Abe KT, Wang JH, Pasculescu A, Maltseva M, Rocheleau L, Pelchat M, Fazel-Zarandi M, Iskilova M, Barrios-Rodiles M, Bennett L, Yau K, Cholette F, Mesa C, Li AX, Paterson A, Hladunewich MA, Goodwin PJ, Wrana JL, Drews SJ, Mubareka S, McGeer AJ, Kim J, Langlois M-A, Gingras A-C, Durocher Y. A “Made-in-Canada” serology solution for profiling humoral immune responses to SARS-CoV-2 infection and vaccinationbioRxiv. 2021 Oct 26. doi: 10.1101/2021.10.25.21265476v1

Demone JJ, Maltseva M, Nourimand M, Nasr-Sharif M, Galipeau Y, Langlois MA, MacLean AM. Plant-based production of SARS-CoV-2 antigens for use in a subunit vaccine. bioRxiv. 2021 Jan 1. doi: 10.1101/2021.10.17.464700

Mithani SS, Bota AB, Zhu DT, Wilson K. A scoping review of global vaccine certificate solutions for COVID-19. Hum Vaccin Immunother. 2021 Oct 6.  doi:10.1080/21645515.2021.1969849

Brumme ZL, Mwimanzi F, Lapointe HR, Cheung P, Sang Y, Duncan MC, Yaseen F, Agafitei O, Ennis S, Ng K, Basra S, Lim LY, Kalikawe R, Speckmaier S, Moran-Garcia N, Young L, Ali H, Ganase B, Umviligihozo G, Omondi FH, Atkinson K, Sudderuddin H, Toy J, Sereda P, Burns L, Costiniuk CT, Cooper C, Anis AH, Leung V, Holmes D, DeMarco ML, Simons J, Hedgcock M, Romney MG, Barrios R, Guillemi S, Brumme CJ, Pantophlet R, Montaner JSG, Niikura M, Harris M, Hull M, Brockman MA. Humoral immune responses to COVID-19 vaccination in people living with HIV on suppressive antiretroviral therapy. medRxiv. 2021 Oct 4. doi: https://doi.org/10.1101/2021.10.03.21264320

Merkley E, Loewen PJ. Assessment of Communication Strategies for Mitigating COVID-19 Vaccine-Specific Hesitancy in CanadaJAMA Netw Open. 2021 Sep 1;4(9):e2126635. doi: 10.1001/jamanetworkopen.2021.26635

Saeed S, O’Brien SF, Abe K, Yi O, Rathod B, Wang J, Fazel-Zarandi M, Tuite A, Fisman D, Wood H, Colwill K, Gingras A-C, Drews S. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence: Navigating the absence of a gold standard. PLOS ONE. 2021 Sep 23. doi: https://doi.org/10.1371/journal.pone.0257743

Ayoubkhani D, Pawelek P, Gaughan C. Technical article: Updated estimates of the prevalence of post-acute symptoms among people with coronavirus (COVID-19) in the UK: 26 April 2020 to 1 August 2021. UK Office for National Statistics. Released: 16 September 2021

SARS-CoV-2–Reactive Mucosal B Cells in the Upper Respiratory Tract of Uninfected Individuals. J Immunol October 4, 2021, ji2100606; DOI: https://doi.org/10.4049/jimmunol.2100606

Antia R, Halloran ME. Transition to endemicity: Understanding COVID-19, Immunity (2021). Immunity, 24 september 2021 doi: 10.1016/j.immuni.2021.09.019

Vinh DC, Gouin JP, Cruz-Santiago D, Canac-Marquis M, Bernier S, Bobeuf F, Sengupta A, Brassard JP, Guerra A, Dziarmaga R, Perez A, Sun Y, Li Y, Roussel L, Langelier J, Ke D, Arnoldd C, Pelchat M, Langlois MA, Zhang X, Mazer BD. Real-world serologic responses to Extended-interval and Heterologous COVID-19 mRNA vaccination in Frail Elderly-Interim report from a prospective observational cohort study. medRxiv 21 Sept 2021; doi: 10.1101/2021.09.16.21263704

Luong L, Beder M, Nisenbaum R, Orkin A, Wong J, Damba C, Emond R, Lena S, Wright V, Loutfy M, Bruce-Barrett C, Cheung W, Cheung YK, Williams V, Vanmeurs M, Boozary A, Manning H, Hester J, Hwang SW, 2021. Prevalence of SARS-CoV-2 infection among people experiencing homelessness in Toronto during the first wave of the COVID-19 pandemic. medRxiv, September 26, 2021. doi:10.1101/2021.09.21.21263713

Saeed S, O’Brien SF, Abe K, Yi O, Rathod B, Wang J, Fazel-Zarandi M, Tuite A, Fisman D, Wood H, Colwill K, Gingras A-C, Drews S. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence: Navigating the absence of a gold standard. PLOS ONE. 2021 Sep 23. doi: https://doi.org/10.1371/journal.pone.0257743

Skowronski DM, Setayeshgar S, Zou M, Prystajecky N, Tyson JR, Sbihi H, Fjell CD, Galanis E, Naus M, Patrick DM, El Adam S. Comparative single-dose mRNA and ChAdOx1 vaccine effectiveness against SARS-CoV-2, including early variants of concern: a test-negative design, British Columbia, Canada. medRxiv. 2021 Sept 22. doi : 10.1101/2021.09.20.21263875

Yanling Liu, Patrick Budylowski, Shilan Dong, Zhijie Li, Sofiya Goroshko, Leslie Y. T. Leung, Eyal Grunebaum, Paolo Campisi, Evan J. Propst, Nikolas E. Wolter, James M. Rini, Amin Zia, Mario Ostrowski and Götz R. A. Ehrhardt. SARS-CoV-2–Reactive Mucosal B Cells in the Upper Respiratory Tract of Uninfected Individuals. J Immunol October 4, 2021, ji2100606; DOI: https://doi.org/10.4049/jimmunol.2100606

Vinh DC, Gouin JP, Cruz-Santiago D, Canac-Marquis M, Bernier S, Bobeuf F, Sengupta A, Brassard JP, Guerra A, Dziarmaga R, Perez A, Sun Y, Li Y, Roussel L, Langelier J, Ke D, Arnoldd C, Pelchat M, Langlois MA, Zhang X, Mazer BD. Real-world serologic responses to Extended-interval and Heterologous COVID-19 mRNA vaccination in Frail Elderly-Interim report from a prospective observational cohort study. medRxiv 21 Sept 2021;doi: 10.1101/2021.09.16.21263704

Saeed S, O’Brien SF, Abe K, Yi O, Rathod B, Wang J, Fazel-Zarandi M, Tuite A, Fisman D, Wood H, Colwill K, Gingras A-C, Drews S. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence: Navigating the absence of a gold standard. PLOS ONE. 2021 Sep 23. doi: https://doi.org/10.1371/journal.pone.0257743

Tang X, Gelband H, Nagelkerke N, Bogoch II, Brown P, Morawski E, Tam T. COVID-19 vaccination intention during early vaccine rollout in Canada: a nationwide online surveyThe Lancet Regional Health – Americas 2021:100055. doi : 10.1016/j.lana.2021.100055

Dick DW, Childs L, Feng Z, Li J, Röst G, Buckeridge DL, Ogden NH, Heffernan JM. Fall 2021 Resurgence and COVID-19 Seroprevalence in Canada Modelling waning and boosting COVID-19 immunity in Canada A Canadian Immunization Research Network StudymedRxiv 2021.08.17.21262188; doi : 10.1101/2021.08.17.21262188

Hogan CA, Jassem AN, Sbihi H, Joffres Y, Tyson JR, Noftall K, Taylor M, Lee T, Fjell C, Wilmer A, Galbraith J, Romney MG, Henry B, Krajden M, Galanis E, Prystajecky N, Hoang LMN. Rapid Increase in SARS-CoV-2 P.1 Lineage Leading to Codominance with B.1.1.7 Lineage, British Columbia, Canada, January-April 2021. Emerg Infect Dis. Le 13 août 2021;27(11). doi : 10.3201/eid2711.211190

Lee BE, Sikora C, Faulder D, Risling E, Little LA, Qiu Y, Gao T, Bulat R, Craik S, Hrudey SE, Ohinmaa A, Estabrooks C, Gingras AC, Charlton C, Kim J, Wood H, Robinson A, Kanji JN, Zelyas N, O’Brien SF, Drews S, Pang XL. Early Warning and Rapid Public Health Response to Prevent COVID-19 outbreaks in long-term care facilities (LTCF) by Monitoring SARS-CoV-2 RNA in LTCF site-specific Sewage Samples and Assessment of Antibodies Response in this Population – Prospective Study Protocol. BMJ Open Le 20 août 2021;11(8):e052282. doi : 10.1136/bmjopen-2021-052282.

Rais Y, Fu Z, Drabovich AP. Mass spectrometry-based proteomics in basic and translational research of SARS-CoV-2 coronavirus and its emerging mutants. Clin Proteomics 2021;18:19. doi : 10.1186/s12014-021-09325-x

Tang X, Sharma A, Pasic M, Brown P, Colwill K, Gelband H, Birnboim HC, Nagelkerke N, Bogoch II, Bansal A, Newcombe L, Slater J, Rodriguez PS, Huang G, Fu SH, Meh C, Wu CN, Kaul R, Langlois MA, Morawski E, Hollander A, Eliopoulos D, Aloi B, Lam T, Abe KT, Rathod B, Fazel-Zarandi M, Wang J, Iskilova M, Pasculescu A, Caldwell L, Barrios-Rodiles M, Mohammed-Ali Z, Vas N, Santhanam DR, Cho ER, Qu K, Jha S, Jha V, Suraweera W, Malhotra V, Mastali K, Wen R, Sinha S, Reid A, Gingras AC, Chakraborty P, Slutsky AS, Jha P. SARS-CoV-2 Seroprevalence During the First and Second Pandemic Waves in Canada. Soc Sci Res Net. Le 12 août 2021. doi : http://dx.doi.org/10.2139/ssrn.3903944

Breznik JA, Zhang A, Huynh A, Miller MS, Nazy I, Bowdish DME, Costa AP, COVID in Long Term Care Study Group. Antibody responses 3-5 months post-vaccination with mRNA-1273 or BNT163b2 in nursing home residents. medRxiv. Le 19 août 2021. doi : https://doi.org/10.1101/2021.08.17.21262152

Abe KT, Hu Q, Mozafarihashjin M, Samson B, Rathod B, Chao G, Wang JH, Iskilova M, Pasculescu A, Fazel-Zarandi M, Li A, Paterson A, Green K, Gilbert L, Barati S, Haq N, Takaoka A, Takaoka JG, De Launay KQ, Fahim C, Sheikh-Mohamed S, Arita Y, Durocher Y, Marcusson EG, Gommerman JL, Ostrowski M, Colwill K, Straus SE, Wood H, McGeer AJ, Gingras AC. Neutralizing antibody responses to SARS-CoV-2 variants in vaccinated Ontario long-term care home residents and workersmedRxiv. Le 8 août 2021. doi : www.medrxiv.org/content/10.1101/2021.08.06.21261721v1

Sheikh-Mohamed S, Chao GYC, Isho B, Zuo M, Nahass GR, Salomon-Shulman RE, Blacker G, Fazel-Zarandi M, Rathod B, Colwill K, Jamal A, Li Z, Quin de Launay K, Takaoka A, Garnham-Takaoka J, Fahim C, Paterson A, Xinliu Li A, Haq N, Barati S, Gilbert L, Green K, Mozafarihashjin M, Samaan P, Siqueira W, Mubareka S, Ostrowski M, Rini JM, Rojas OL, McGeer A, Weissman IL, Caspi Tal M, Straus S, Gingras AC, Gommerman JL. A mucosal antibody response is induced by intra-muscular SARS-CoV-2 mRNA vaccination. medRxiv 2021.08.01.21261297; doi : https://doi.org/10.1101/2021.08.01.21261297

Nikiforuk AM, McMillan B, Bartlett SR, Márquez AC, Pidduck T, Kustra J, Goldfarb DM, Barakauskas V, Sinclair G, Patrick DM, Sadarangani M, Ogilvie GS, Morshed M, Sekirov, Jassem AN. Performance of Immunoglobulin G Serology on Finger Prick Capillary Dried Blood Spot Samples to Measure SARS-CoV-2 Seroconversion and Humoral Immunogenicity of COVID-19 Vaccination. medRxiv. Le 31 juillet 2021. doi : https://doi.org/10.1101/2021.07.29.21261156

Khana MS, Allison PJ, Siqueira WL, McNally ME, Glogauer M, Quinonez C, Madathil SA. Prevalence of COVID-19 among Canadian Dentists in August 2020. Affiche 1917, présentée à la 99e séance générale du congrès de l’Association internationale de recherches dentaires (AIRD). Du 21 au 24 juillet 2021.

Seth R, Allison PJ, Siqueira WL, McNally ME, Quinonez C, Glogauer M, Madathil SA. COVID-19 Anxiety syndrome among Canadian dentists during the pandemic. Affiche 1918, présentée à la 99e séance générale du congrès de l’Association internationale de recherches dentaires (AIRD). Du 21 au 24 juillet 2021.

Hall VG, Ferreira VH, Ierullo M, Ku T, Marinelli T, Majchrzak-Kita B, Yousuf A, Kulasingam V, Humar A, Kumar D. Humoral and Cellular immune response and Safety of 2-dose SARS-CoV-2 mRNA-1273 (Moderna) vaccine in Solid Organ Transplant Recipients. Am J Transplant. date Juillet 2021 volume(number):pages. doi : link

Li X, Vanderloo LM, Maguire JL, Keown-Stoneman CDG, Aglipay M, Anderson LN, Cost KT, Charach A, Vanderhout SM, Birken CS, TARGet Kids! Collaboration, 2021. Public health preventive measures and child health behaviours during COVID-19: a cohort study. Can J Public Health. doi :10.17269/s41997-021-00549-w

Galipeau Y, Siragam V, Laroche G, Marion E, Greig M, McGuinty M, Booth RA, Durocher Y, Cuperlovic-Culf M, Bennett SAL, Crawley AM, Giguère P, Cooper C, Langlois M-A. Relative Ratios of Human Seasonal Coronavirus Antibodies Predict the Efficiency of Cross-Neutralization of SARS-CoV-2 Spike Binding to ACE2. MedRxiv 2021.07.16.21260079; doi : https://doi.org/10.1101/2021.07.16.21260079

McKinnon B, Quach C, Dubé E, Tuong Nguyen C, Zinszer K. Social inequalities in COVID-19 vaccine acceptance and uptake for children and adolescents in Montreal, Canada: a cross-sectional studydoi :https://doi.org/10.1101/2021.05.08.21256831

Williams C, Al-Bargash D, Macalintal C, Stuart R, Seth A, Latham J, Gitterman L, Fedsin S, Godoy M, Kozak R, Guthrie JL, Wood H, McGeer A, Hota S, Rea E. COVID-19 Outbreak Associated with a SARS-CoV-2 P. 1 Lineage in a Long-Term Care Home after Implementation of a Vaccination Program–Ontario, April-May 2021Clin Infect Dis. Le 8 juillet 2021. DOI : https://doi.org/10.1093/cid/ciab617

Duarte N, D’Mello S, Duarte NA, Rocco S, Wyk JV, Pillai AA, Liu M, Williamson T, Arora RK. Uptake of SARS-CoV-2 workplace testing programs, March 2020 to March 2021. medRxiv. Le 3 juillet 2021. doi: 10.1101/2021.06.29.21259730.

Nasreen S, He S, Chung H, Brown KA, Gubbay JB, Buchan SA, Wilson SE, Sundaram ME, Fell DB, Chen B, Calzavara A, Austin PC, Schwartz KL, Tadrous M, Wilson K, Kwong JC. Effectiveness of COVID-19 vaccines against variants of concern, Canada. medRxiv. Le 3 juillet 2021. doi: 10.1101/2021.06.28.21259420.

Bobrovitz N, Arora RK, Cao C, Boucher E, Liu M, Donnici C, Yanes-Lane M, Whelan M, Perlman-Arrow S, Chen J, Rahim H, Ilincic N, Segal M, Duarte N, Van Wyk J, Yan T, Atmaja A, Rocco S, Joseph A, Penny L, Clifton DA, Williamson T, Yansouni CP, Evans TG, Chevrier J, Papenburg J, Cheng MP. Global seroprevalence of SARS-CoV-2 antibodies: A systematic review and meta-analysis. PLOS One. 16(6):e0252617. doi : 10.1371/journal.pone.0252617.

Law JC, Girard M, Chao GYC, Ward LA, Isho B, Rathod B, Colwill K, Li Z, Rini JM, Yue FY, Mubareka S, McGeer AJ, Ostrowski MA, Gommerman JL, Gingras AC, Watts TH. Immunity to SARS-CoV-2 persists 9 months post-symptoms with an altered T cell phenotype compared to influenza A virus-specific memory. medrxiv. Le 10 juin 2021. doi: 10.1101/2021.06.08.21258518.

Goldfarb DM, Mâsse LC, Watts AW, Hutchison SM, Muttucomaroe L, Bosman ES, Barakauskas VE, Choi A, Irvine MA, Reicherz F, Coombs D, O’Reilly C, Sediqi S, Razzaghian HR, Sadarangani M, O’Brien SF, Lavoie PM. SARS-CoV-2 seroprevalence among Vancouver public school staff in British Columbia, Canada. medRxiv. Le 18 juin 2021. doi:10.1101/2021.06.16.21258861.

Kinloch NN, Ritchie G, Dong W, Cobarrubias KD, Sudderuddin H, Lawson T, Matic N, Montaner JSG, Leung V, Romney MG, Lowe CF, Brumme CJ, Brumme ZL. SARS-CoV-2 RNA quantification using droplet digital RT-PCRJ Mol Diagn. Le 29 mai 2021. doi : 10.1016/j.jmoldx.2021.04.014.

Chung H, He S, Nasreen S, Sundaram ME, Buchan SA, Wilson SE, Chen B, Calzavara A, Fell DB, Austin PC, Wilson K, Schwartz KL, Brown KA, Gubbay JB, Basta NE, Mahmud SM, Righolt CH, Svenson LW, Macdonald SE, Janjua NZ, Tadrous M, Kwong JC. Effectiveness of BNT162b2 and mRNA-1273 COVID-19 vaccines against symptomatic SARS-CoV-2 infection and severe COVID-19 outcomes in Ontario, Canada. BMJ.doi : https://doi.org/10.1136/bmj.n1943 

Costa AP, Manis DR, Jones A, Stall NM, Brown KA, Boscard V, Castellino A, Heckman GA, Hillmer MP, Ma C, Pham P, Rais S, Sinha SK, Poss JW. Facteurs de risque d’éclosion de SRAS-CoV-2 dans les résidences pour aînés en Ontario, au Canada: étude de cohorte à l’échelle de la population. JAMC. Le 21 juin 2021;193(25):E969-77. doi: 10.1503/cmaj.202756-f.

Goldfarb DM, Mâsse LC, Watts AW, Hutchison SM, Muttucomaroe L, Bosman ES, Barakauskas VE, Choi A, Irvine MA, Reicherz F, Coombs D, O’Reilly C, Sediqi S, Razzaghian HR, Sadarangani M, O’Brien SF, Lavoie PM. SARS-CoV-2 seroprevalence among Vancouver public school staff in British Columbia, Canada. medRxiv. Le 18 juin 2021. doi: 10.1101/2021.06.16.21258861.

Law JC, Girard M, Chao GYC, Ward LA, Isho B, Rathod B, Colwill K, Li Z, Rini JM, Yue FY, Mubareka S, McGeer AJ, Ostrowski MA, Gommerman JL, Gingras A-C, Watts TH. Immunity to SARS-CoV-2 persists 9 months post-symptoms with an altered T cell phenotype compared to influenza A virus-specific memory. medRxiv. Le 10 juin 2021. doi: 10.1101/2021.06.08.21258518.

Matic N, Lowe CF, Ritchie G, Stefanovic A, Lawson T, Jang W, Young M, Dong W, Brumme ZL, Brumme CJ, Leung V, Romney MG. Rapid detection of SARS-CoV-2 variants of concern identifying a cluster of B.1.1.28/P.1 variant in British Columbia, Canada. Emerg Infect Dis. Le juin 2021;27(6):1673-1676. doi: 10.3201/eid2706.210532.

Chung H, He S, Nasreen S, Sundaram ME, Buchan SA, Wilson SE, Chen B, Calzavara A, Fell DB, Austin PC, Wilson K, Schwartz KL, Brown KA, Gubbay JB, Basta NE, Mahmud SM, Righolt CH, Svenson LW, Macdonald SE, Janjua NZ, Tadrous M, Kwong JC. Effectiveness of BNT162b2 and mRNA-1273 COVID-19 vaccines against symptomatic SARS-CoV-2 infection and severe COVID-19 outcomes in Ontario, Canada. Le 28 mai 2021. doi: 10.1101/2021.05.24.21257744.

Saeed S, O’Brien SF, Abe K, Yi O, Rathod B, Wang J, Fazel-Zarandi M, Tuite A, Fisman D, Wood H, Colwill K, Gingras A-C, Drews S. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence: Navigating the absence of a gold standard. medRxiv. 2021 May 12. doi: 10.1101/2021.05.11.21256992.

Anand SP, Prévost J, Nayrac M, Beaudoin-Bussières G, Benlarbi M, Gasser R, Brassard N, Laumaea A, Gong SY, Bourassa C, Brunet-Ratnasingham E, Medjahed E, Gendron-Lepage G, Goyette G, Gokool L, Morrisseau C, Bégin P, Martel-Laferrière V, Tremblay C, Richard J, Bazin R, Duerr R, Kaufmann D, Finzi A.  Longitudinal analysis of humoral immunity against SARS-CoV-2 Spike in convalescent individuals up to 8 months post-symptom onset. Cell Rep Med. Le 4 mai 2021. doi: 10.1016/j.xcrm.2021.100290.

Tang X, Gelband H, Nagelkerke N, Bogoch I, Brown PE, Morawski E, Lam T, Reid A, Jha P. Quantifying COVID-19 vaccination hesitancy during early vaccination rollout in Canada. medRxiv [Preprint]. Le 2 mai 2021. doi: 10.1101/2021.04.29.21256333.

Flood CM, Thomas B, Wilson K. Vaccination obligatoire des travailleurs de la santé: analyse juridique et politique. CMAJ. Le 26 avril 2021 Avr. 26;193(17):E629-33. doi: 10.1503/cmaj.202755-f.

Huynh A, Arnold DM, Smith JW, Moore JC, Zhang A, Chagla Z, Harvey BJ, Stacey HD, Ang JC, Clare R, Ivetic N, Chetty VT, Bowdish DME, Miller MS, Kelton JG, Nazy I. Characteristics of anti-SARS-CoV-2 antibodies in recovered COVID-19 subjects. Viruses. Le 16 avril 2021. 16;13(4):697. doi: 10.3390/v13040697.

Zinszer K, McKinnon B, Bourque N, Zahreddine M, Charland K, Papenburg J, Fortin G, Hamelin ME, Saucier A, Apostolatos A, Pierce L, Savard-Lamothe A, Carbonneau J, Conrod P, Haley N, Laurin I, Boivin G, Serres GD, Quach C. Seroprevalence of anti-SARS-CoV-2 antibodies among school and daycare children and personnel: Protocol for a cohort study in Montreal, Canada. medRxiv [Preprint]. Le 16 avril 2021. doi: 10.1101/2021.04.14.21255499.

Brockman MA, Mwimanzi F, Sang Y, Ng K, Agafitei O, Ennis S, Lapointe H, Young L, Umviligihozo G, Burns L, Brumme CJ, Leung V, Montaner JSG, Holmes D, DeMarco M, Simons J, Niikura M, Pantophlet R, Romney MG, Brumme ZL. Weak humoral immune reactivity among elderly residents of long-term care facilities following one dose of BNT162b2 mRNA COVID-19 vaccine. medRxiv [Preprint]. Le 24 mars 2021. doi: 10.1101/2021.03.17.21253773

Irfan Ullah, Jérémie Prévost, Mark S Ladinsky, Helen Stone, Maolin Lu, Sai Priya Anand, Guillaume Beaudoin-Bussières, Mehdi Benlarbi, Shilei Ding, Romain Gasser, Corby Fink, Yaozong Chen, Alexandra Tauzin, Guillaume Goyette, Catherine Bourassa, Halima Medjahed, Matthias Mack, Kunho Chung, Craig B Wilen, Gregory A. Dekaban, Jimmy D. Dikeakos, Emily A. Bruce, Daniel E Kaufmann, Leonidas Stamatatos, Andrew T. McGuire, Jonathan Richard, Marzena Pazgier, Pamela J. Bjorkman, Walther Mothes, Andrés Finzi, Priti Kumar, Pradeep D. Uchil. Live imaging of SARS-CoV-2 infection in mice reveals neutralizing antibodies require Fc function for optimal efficacy. bioRxiv [Preprint]. Le 22 mars 2021. doi: 10.1101/2021.03.22.436337

Brunet-Ratnasingham E, Anand SP, Gantner P, Moquin-Beaudry G, Dyachenko A, Brassard N, Beaudoin-Bussières G, Pagliuzza A, Gasser R, Benlarbi M, Point F, Prévost J, Laumaea A, Niessl J, Nayrac M, Sannier G, Boutin M, Descôteux-Dinelle J, Gendron-Lepage G, Goyette G, Bourassa C, Medjahed H, Orban C, Butler-Laporte G, Morrison D, Zhou S, Nakanishi T, Laurent L, Richard J, Dubé M, Fromentin R, Rébillard R-M, Arbour N, Prat A, Larochelle C, Durand M, Richards JB, Chassé M, Tétreault M, Chomont N, Finzi A, Kaufmann DE. Integrated immunovirological profiling validates plasma SARS-CoV-2 RNA as an early predictor of COVID-19 mortality. medRxiv [Preprint]. Le 20 mars 2021. doi: 10.1101/2021.03.18.21253907

Majdoubi A, Michalski C, O’Connell SE, Dada S, Narpala S, Gelinas J, Mehta D, Cheung C, Winkler D, Basappa M, Liu  AC, Görges M, Barakauska VE, Irvine M, Mehalko J, Esposito D, Sekirov I, Jassem AN, Goldfarb DM, Pelech S, Douek DC, McDermott AB, Lavoie PM. A majority of uninfected adults show pre-existing antibody reactivity against SARS-CoV-2. JCI Insight. Le 15 mars 2021. doi: 10.1172/jci.insight.146316.

Castonguay N, Zhang W, Langlois M-A. Meta-analysis of the dynamics of the emergence of mutations and variants of SARS-CoV-2. medRxiv [Preprint]. Le 8 mars 2021. doi: 10.1101/2021.03.06.21252994

Tang X, Sharma A, Pasic M, Colwill K, Birnboim Ch, Nagelkerke Nico, Bogoch I, Schultz C, Newcombe L, Slater J, Rodriguez P, Huang G, Fu SH,  Meh C, Wu ChN,  Kaul R, Langlois MA, M E, Hollander A, Eliopoulos D, Aloi B, Lambe T, AbeK, Caldwell L, Barrios-Rodiles M,  Fazel-Zarandi M, Weingust R, Wang J, Rathod B, Santhanam DR, Cho ER, Qu K, Jha S, Jha V, Suraweera W,  Wen R, Sinha SR, Gingras AC, Chakraborty P, Slutsky  AS, Jha P. COVID symptoms, seroprevalence, and mortality during the first wave of SARS-CoV-2 in Canada. medRxiv [Preprint]. Le 5 mars 2021. doi: 10.1101/2021.03.04.21252540.

K Wilson and C Flood. Implementing digital passports for SARS-CoV-2 immunization in Canada. CMAJ. Le 2 mars 2021;193(10). doi: 10.1503/cmaj.210244.

Rébillard RM, Charabati M, Grasmuck C, Filali-Mouhim A, Tastet O, Brassard N, Daigneault A, Bourbonnière L, Anand SP, Balthazard R, Beaudoin-Bussières G, Gasser R, Benlarbi M, Carmena Moratalla A, Carpentier Solorio Y, Boutin M, Farzam-Kia N, Descôteaux-Dinelle J, Fournier AP, Gowing EM, Laumaea A, Jamann H, Lahav B, Goyette G, Lemaître F, Mamane VH, Prévost J, Richard J, Thai K, Cailhier JF, Chomont N, Finzi A, Chassé M, Durand M, Arbour N, Kaufmann DE, Prat A, Larochelle C. Identification of SARS-CoV-2-specific immune alterations in acutely ill patients. J Clin Invest. Le 26 février 2021;26:145853. doi: 10.1172/JCI145853

Nazy I, Jevtic SD, Moore JC, Huynh A, Smith JW, Kelton JG, Arnold DM. Platelet-activating immune complexes identified in critically ill COVID-19 patients suspected of heparin-induced thrombocytopenia. J Thromb Haemost. Le 27 février 2021. doi: 10.1111/jth.15283.

Papenburg J , Cheng MP , Corsini R, Caya C, Mendoza E, Manguiat K, Lindsay LF , Wood H, Drebot MA, Dibernardo A , Zaharatos G , Bazin R, Gasser R, Benlarbi M , Gendron-Lepage G, Beaudoin-Bussières G, Prévost J, Finzi A, Ndao M, Yansouni C.  Evaluation of a commercial culture-free neutralization antibody detection kit for severe acute respiratory syndrome-related coronavirus-2 and comparison with an anti-RBD ELISA assay. medRxiv [Preprint]. Le 20 février 2021. doi: 10.1101/2021.01.23.21250325.

Anand SP, Prévost J, Richard J, Perreault J, Tremblay T, Drouin M, Fournier MJ, Lewin A, Bazin R, Finzi A. High-throughput detection of antibodies targeting the SARS-CoV-2 Spike in longitudinal convalescent plasma samples. Transfusion. Le 18 février 2021. doi: 10.1111/trf.16318.

Gasser R, Cloutier M, Prévost J, Fink C, Ducas É, Ding S, Dussault N, Landry P, Tremblay T, Laforce-Lavoie A, Lewin A, Beaudoin-Bussières G, Laumaea A, Medjahed H, Larochelle C, Richard J, Dekaban GA, Dikeakos JD, Bazin R, Finzi A. Major role of IgM in the neutralizing activity of convalescent plasma against SARS-CoV-2. Cell Rep. Le février 2021. 10:108790. doi: 10.1016/j.celrep.2021.108790.

Flood C, Thomas B, Wilson K. Mandatory vaccination for health care workers: an analysis of law and policy. CMAJ. Le 8 février 2021. 8;193(6). doi.org/10.1503/cmaj.202755.

Saeed S, Drews SJ, Pambrun C, Yi QL, Osmond L, O’Brien SF. SARS‐CoV‐2 seroprevalence among blood donors after the first COVID‐19 wave in Canada. Transfusion. Le 1 février 2021. doi: 10.1111/trf.16296.

Bolotin S, Tran V, Osman S, Brown KA, Buchan SA, Joh E, Deeks SL, Allen VG. SARS-CoV-2 seroprevalence survey estimates are affected by anti-nucleocapsid antibody decline. J Infect Dis. Le 5 janvier 2021:jiaa796. doi: 10.1093/infdis/jiaa796.

Law JC, Koh WH, Budylowski P, Lin J, Yue F, Abe KT, Rathod B, Girard M, Li Z, Rini JM, Mubareka S, McGeer A, Chan AK, Gingras AC, Watts TH, A Ostrowski M. Systematic examination of antigen-specific recall T cell responses to SARS-CoV-2 versus influenza virus reveals a distinct inflammatory profile. J Immunol. Le 1 janvier 2021;206(1):37-50. doi: 10.4049/jimmunol.2001067.

Lu M, Uchil PD, Li W, Zheng D, Terry DS, Gorman J, Shi W, Zhang B, Zhou T, Ding S, Gasser R, Prévost J, Beaudoin-Bussières G, Anand SP, Laumaea A, Grover JR, Liu L, Ho DD, Mascola JR, Finzi A, Kwong PD, Blanchard SC, Mothes W. Real-time conformational dynamics of SARS-CoV-2 spikes on virus particles. Cell Host & Microbe. Le 9 décembre 2020;28(6):880-891. doi: 0.1016/j.chom.2020.11.001.

Ding S, Laumaea A, Benlarbi M, Beaudoin-Bussières G, Gasser R, Medjahed H, Pancera M, Stamatatos L, McGuire AT, Bazin R, Finzi A. Antibody binding to SARS-CoV-2 S glycoprotein correlates with but does not predict neutralization. Viruses. Le 26 octobre 2020; 12(11):1214. doi: 10.3390/v12111214.

Prévost J, Gasser R, Beaudoin-Bussières G, Richard J, Duerr R, Laumaea A, Anand SP, Goyette G, Benlarbi M, Ding S, Medjahed H, Lewin A, Perreault J, Tremblay T, Gendron-Lepage G, Gauthier N, Carrier M, Marcoux D, Piché A, Lavoie M, Benoit A, Loungnarath V, Brochu G, Haddad E, Stacey HD, Miller MS, Desforges M, Talbot PJ, Maule GTG, Côté M, Therrien C, Serhir B, Bazin R, Roger M, Finzi A. Cross-sectional evaluation of humoral responses against SARS-CoV-2 Spike. Cell Rep Med. Le 20 octobre 2020;1(7):100126. doi: 10.1016/j.xcrm.2020.100126.

Beaudoin-Bussières G, Laumaea A, Anand SP, Prévost J, Gasser R, Goyette G, Medjahed H, Perreault J, Tremblay T, Lewin A, Gokool L, Morrisseau C, Bégin P, Tremblay C, Martel-Laferrière V, Kaufmann D, Richard J, Bazin R, Finzi A. Decline of humoral responses against SARS-CoV-2 spike in convalescent individuals. mBio. Le 16 octobre 2020. doi: 10.1128/mBio.02590-20.

Anand SP, Chen Y, Prévost J, Gasser R, Beaudoin-Bussières G, Abrams CF, Pazgier M, Finzi A. Interaction of human ACE2 to membrane-bound SARS-CoV-1 and SARS-CoV-2 S glycoproteins. Viruses. Le 29 septembre 2020;12(10):1104. doi: 10.3390/v12101104.

Arora RK, Joseph A, Van Wyk J, Rocco S, Atmaja A, May E, Yan T, Bobrovitz N, Chevrier J, Cheng MP, Williamson T. SeroTracker: a global SARS-CoV-2 seroprevalence dashboard. Lancet Infect Dis. Le aout 2020. doi: 10.1016/S1473-3099(20)30631-9

Publications de nos experts

Stephen B. Freedman and James D. Kellner. Protecting Canada’s children from the consequences of the fourth wave of the COVID-19 pandemic. CMAJ September 27, 2021 193 (38) E1500-E1502; DOI: https://www.cmaj.ca/content/193/38/E1500

Vinh DC, Abel L, Bastard P, Cheng MP, Condino-Neto A, Gregersen PK, Haerynck F, Cicalese MP, Hagin D, Soler-Palacín P, Planas AM. Harnessing Type I IFN Immunity Against SARS-CoV-2 with Early Administration of IFN-β. Journal of Clinical Immunology. 2021 Jun 8:1-8.

Yang J, D’Souza R, Kharrat A, Fell DB, Snelgrove JW, Murphy KE, Shah P.. COVID‐19 pandemic and population‐level pregnancy and neonatal outcomes: a living systematic review and meta‐analysisActa Obstet et Gynecol Scand 2021;100:1756–70. doi:10.1111/aogs.14206

Drouin O, Moore Hepburn C, Farrar DS, Baerg K, Chan K, Cyr C, Donner EJ, Embree JE, Farrell C, Forgie S, Giroux R, Kang KT, King M, Laffin M, Luu TM, Orkin J, Papenburg J, Pound CM, Price VE, Purewal R, Sadarangani M, Salvadori MI, Top KA, Viel-Thériault I, Kakkar F et Morris SK. Characteristics of children admitted to hospital with acute SARS-CoV-2 infection in Canada in 2020CMAJ September 27, 2021 193 (38) E1483-E1493; DOI: https://www.cmaj.ca/content/193/38/E1483

Skowronski DM, Setayeshgar S, Zou M, Prystajecky N, Tyson JR, Sbihi H, Fjell CD, Galanis E, Naus M, Patrick DM, El Adam S. Comparative single-dose mRNA and ChAdOx1 vaccine effectiveness against SARS-CoV-2, including early variants of concern: a test-negative design, British Columbia, CanadamedRxiv. 2021 Sept 22. doi : 10.1101/2021.09.20.21263875

Luong L, Beder M, Nisenbaum R, Orkin A, Wong J, Damba C, Emond R, Lena S, Wright V, Loutfy M, Bruce-Barrett C, Cheung W, Cheung YK, Williams V, Vanmeurs M, Boozary A, Manning H, Hester J, Hwang SW, 2021. Prevalence of SARS-CoV-2 infection among people experiencing homelessness in Toronto during the first wave of the COVID-19 pandemic. medRxiv, September 26, 2021. doi:10.1101/2021.09.21.21263713

Top KA, Bettinger JA, Kwong JC, Wilson SE, Hapuhennedige S. Enhancing Canada’s Vaccine Safety Surveillance for COVID-19 Vaccination Programs. CANvax. 2021 Sep 8. https://canvax.ca/brief/enhancing-canadas-vaccine-safety-surveillance-covid-19-vaccination-programs / Top KA, Bettinger JA, Kwong JC, Wilson SE, Hapuhennedige S. Renforcement de la surveillance de l’innocuité des vaccins dans les programmes de vaccination contre la COVID-19 au Canada. CANvax. 2021 Sep 8. https://canvax.ca/fr/brief/renforcement-de-la-surveillance-de-linnocuite-des-vaccins-dans-les-programmes-de-vaccination

Stone M, Grebe E, Sulaeman H, Di Germanio C, Dave H, Kelly K, Biggerstaff B, Crews BO, Tran N, Jerome KR, Denny TN, Hogema B, Destree M, Jones JM, Thornburg N, Simmons G, Krajden M, Kleinman S, Dumont LJ, Busch MP. Evaluation of commercially available high-throughput SARS-CoV-2 serological assays for serosurveillance and related applications. medRxiv doi: 10.1101/2021.09.04.21262414

Savitz DA, Bengtson AM, Hardy E, Fell DB. Pregnancy and the Risk of Severe COVID-19 Infection: Methodologic Challenges and Research Recommendations. BJOG. 18 Sep 2021. doi: 10.1111/1471-0528.16935.

Velásquez García HA, Wilton J, Smolina K, Chong M, Rasali D, Otterstatter M, Rose C, Prystajecky N, David S, Galanis E, McKee G, Krajden M, Zafar Janjua NZ. Mental health and substance use associated with hospitalization among people with laboratory confirmed diagnosis of COVID-19 in British Columbia: a population-based cohort study. medRxiv. Le 28 août 2021. doi : 10.1101/2021.08.26.21262697

Kaida A, Brotto LA, Murray MCM, Cote HCF, Albert AY, Nicholson V, Gormley R, Gordon S, Booth A, Smith LW, Baaske A, Galea LAM, Sadarangani M, Ogilvie GS. Intention to receive a COVID-19 vaccine by HIV status among a population-based sample of women and gender diverse individuals in British Columbia, Canada. Le 22 août 2021. https://www.medrxiv.org/content/10.1101/2021.08.19.21262249v1 doi : https://doi.org/10.1101/2021.08.19.21262249

Bastard P, …, [Vinh DC] …, et al. Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deathsSci Immunol. Le 19 août 2021;6(62):eabl4340. doi : 10.1126/sciimmunol.abl4340. PMID : 34413139.

Fisman DN, Greer AL, Brankston G, Hillmer M, O’Brien SF, Drews SJ, Tuite AR. COVID-19 Case Age Distribution: Correction for Differential Testing by Age. Ann Intern Med. doi : 10.7326/M20-7003

Sundaram M, Nasreen S, Calzavara A, He S, Chung H, Bronskill SE, Buchan SA, Tadrous M, Tanuseputro P, Wilson W, Wilson S, Kwong JC. Background rates of all-cause mortality, hospitalizations, and emergency department visits among nursing home residents in Ontario, Canada to inform COVID-19 vaccine safety assessments. Vaccine. 2021;39:5265-70. doi : https://doi.org/10.1016/j.vaccine.2021.07.060

Nault L, Marchitto L, Goyette G, Tremblay-Sher D, Fortin C, Martel-Laferrière V, Trottier B, Richard J, Durand M, Kaufmann D, Finzi A, Tremblay C. Covid-19 vaccine immunogenicity in people living with HIV-1. bioRxiv 2021.08.13.456258. doi : https://doi.org/10.1101/2021.08.13.456258

Gobeil PA, Pillet S, Boulay I, Charland N, Lorin A, Cheng M, Vinh D, Boutet P, Van Der Most R, Roman F, Perez MAC, D’Aoust MA, Landry N, Ward BJ. Durability and Cross-Reactivity of Immune Responses Induced by an AS03 Adjuvanted Plant-Based Recombinant Virus-Like Particle Vaccine for COVID-19. medRxiv. Le 1er janvier 2021. doi : 10.1101/2021.08.04.21261507

Groves H, Piché‐Renaud PP, Allen U. The significance and impact of SARS‐CoV‐2 variants of concern in pediatric solid organ transplantation: More unknowns than knownsPediatr Transplant. Le 16 juin 2021. doi : 10.1111/petr.14071

Hall VG, Ferreira VH, Ku T, Ierullo M, Majchrzak-Kita B, Chaparro C, Selzner N, Schiff J, McDonald M, Tomlinson G, Kulasingam V, Kumar D, Humar A. Randomized Trial of a Third Dose of mRNA-1273 Vaccine in Transplant Recipients. N Engl J Med, le 11 août 2021. doi : 10.1056/NEJMc2111462.

Parotto M, Nainan MS, Munblit D, Elhazmi A, Ranzani O, Herridge M. Recovery after prolonged ICU treatment in patients with COVID-1. Lancet Respir Med 2021;9(8):812-4. doi : https://doi.org/10.1016/S2213-2600(21)00318-0

Lewin A, Therrien R, De Serres G, Grégoire Y, Perreault J, Drouin M, Fournier M J, Tremblay T, Beaudoin J, Beaudoin-Bussières G, Prévost J, Gendron-Lepage G, Finzi A, Bernier F, Bazin R, Germain M, Delage G. (2021). SARS-CoV-2 seroprevalence among blood donors in Québec, and analysis of symptoms associated with seropositivity: a nested case-control study. Can J Public Health;112(4) :576–86. https://doi.org/10.17269/s41997-021-00531-6

Xia Y, Ma H, Moloney G, Velásquez García HA, Sirski M, Janjua NZ, Vickers D, Williamson T, Katz A, Yu K, Kustra R, Buckeridge DL, Brisson M, Baral SD, Mishra S, Maheu-Giroux M, 2021. Geographical concentration of COVID-19 cases by social determinants of health in 16 large metropolitan areas in Canada – a cross-sectional study. medRxiv. 2021.07.23.21261039; doi : 10.1101/2021.07.23.21261039

Nourbakhsh S, Fazil A, Li M, Mangat CS, Peterson SW, Daigle J, Langner S, Shurgold J, D’Aoust P, Delatolla R, Mercier E, Pang X, Lee BE, Stuart R, Wijayasri S, Champredon D. A Wastewater-based epidemic model for SARS-CoV-2 with application to three Canadian cities. medRxiv. Le 25 juillet 2021. doi : https://doi.org/10.1101/2021.07.19.21260773

Wilson K, Sher G, Philpott J. Preparing for the next pandemic by creating Canadian Immunization Services. CMAJ 2021;193:E1092–3. doi : 10.1503/cmaj.210670; www.cmaj.ca/content/193/28/E1092

Bolotin S, Wilson S, Murti M. Achieving and sustaining herd immunity to SARS-CoV-2CMAJ Juillet 2021;193(28):E1089; DOI : 10.1503/cmaj.210892

Huynh A, Kelton JG, Arnold DM, Daka M, Nazy I. Antibody epitopes in vaccine-induced immune thrombotic thrombocytopenia. Nature (2021). https://doi.org/10.1038/s41586-021-03744-4

Racey CS, Donken R, Porter I, Albert A, Bettinger JA, Mark J, Bonifacio L, Dawar M, Gagel M, Kling R, Mema S, Mitchell H, Roe I, Ogilvie G, Sadarangani M, 2021. Intentions of public school teachers in British Columbia, Canada to receive a COVID-19 vaccineVaccine: X 8, 100106. doi : 10.1016/j.jvacx.2021.100106

The CONCOR-1 Study Group, CONCOR-1 writing committee, Bégin P, Callum J, Jamula E, Cook R, Heddle NM, Tinmouth A, Zeller MP, Beaudoin-Bussières G, Amorim L, Bazin R, Loftsgard KC, Carl R, Chassé M, Cushing MM, Daneman N, Devine DV, Dumaresq J, Fergusson DA, Gabe C, Glesby MJ, Li N, Liu Y, McGeer A, Robitaille N, Sachais BS, Scales DC, Schwartz L, Shehata N, Turgeon AF, Wood H, Zarychanski R, Finzi A, Arnold DM, for The CONCOR-1 Study Group. Convalescent plasma for hospitalized patients with COVID-19 and the effect of plasma antibodies: a randomized controlled, open-label trial. medRxiv. Le 3 juillet 2021. doi: 10.1101/2021.06.29.21259427.

Abdulnoor M, Eshaghi A, Perusini SJ, Corbeil A, Cronin K, Fittipaldi N, Forbes JD, Guthrie JL, Kus JV, Majury A, Mazzulli T, Melano RG, Olsha R, Sullivan S, Tran V, Patel SN, Allen VG, Gubbay JB. Real-time RT-PCR allelic discrimination assay for detection of N501Y mutation in the spike protein of SARS-CoV-2 associated with variants of concern. medRxiv. Le 2 juillet 2021. doi: 10.1101/2021.06.23.21258782.

Sadarangani M, Marchant A, Kollmann TR. Immunological mechanisms of vaccine-induced protection against COVID-19 in humans. Nat Rev Immunol. Le 1 juillet 2021. doi: 10.1038/s41577-021-00578-z.

Zhang Y, Malekjahani A, Udugama BN, Kadhiresan P, Chen H, Osborne M, Franz M, Kucera M, Plenderleith S, Yip L, Bader GD, Tran V, Gubbay JB, McGeer A, Mubareka S, Chan WCW. Surveilling and tracking COVID-19 patients using a portable quantum dot smartphone device. Nano Lett. Le 23 juin 2021;21(12):5209-5216. doi: 10.1021/acs.nanolett.1c01280.

Bennet SMP, Kaufmann M, Takami K, Sjaarda C, Douchant K, Moslinger E, Wong H, Reed DE, Ellis AK, Vanner S, Colautti RI, Sheth PM. Small-molecule metabolome identifies potential therapeutic targets against COVID-19. medRxiv. Le 18 juin 2021. doi: 10.1101/2021.06.18.21259150.

Greenhawt M, Abrams EM, Shaker M, Chu DK, Kahn D, Akin C, Alqurashi W, Arkwright P, Baldwin JL, Ben-Shoshan M, Bernstein J, Bingeman T, Blumchen K, Byrne A, Bognanni A, Campbell D, Campbell R, Chagla Z, Chan ES, Chan J, Comberiatti P, Dribin TE, Ellis AK, Fleischer DM, Fox A, Frischmeyer-Guerrerio PA, Gagnon R, Grayson MH, Horner CC, Hourihane J, Katelaris CH, Kim H, Kelso JM, Lang D, Ledford D, Levin M, Lieberman J, Loh R, Mack D, Mazer B, Mosnaim G, Munblit D, Mustafa SS, Nanda A, Oppenheimer J, Perrett KP, Ramsey A, Rank M, Robertson K, Shiek J, Spergel JM, Stukus D, Tang MLK, Tracy JM, Turner PJ, Whalen-Browne A, Wallace D, Wang J, Wasserman S, Witty JK, Worm M, Vander Leek TK, Golden DBK. The risk of allergic reaction to SARS-CoV-2 vaccines and recommended evaluation and management: A systematic review, meta-analysis, GRADE assessment, and international consensus approach. J. Allergy Clin. Immunol. Le 18 juin 2021. doi: 10.1016/j.jaip.2021.06.006.

Griffin BD, Chan M, Tailor N, Mendoza EJ, Leung A, Warner BM, Duggan AT, Moffat E, He S, Garnett J, Tran KN, Banadyga L, Albietz A, Tierney K, Audet J, Bello A, Vendramelli R, Boese AS, Fernando L, Lindsay LR, Jardine CM, Wood H, Poliquin G, Strong JE, Drebot M, Safronetz D, Embury-Hyat C, Kobasa D. SARS-CoV-2 infection and transmission in the North American deer mouse. Nat Commun. Le 14 juin 2021;12:3612. doi: 10.1038/s41467-021-23848-9.

Brotto LA, Chankasingh K, Baaske A, Albert A, Booth A, Kaida A, Smith LW, Racey S, Gottschlich A, Murray MCM, Sadarangani M, Ogilvie GS, Galea L. The influence of sex, gender, age, and ethnicity on psychosocial factors and substance use throughout phases of the COVID-19 pandemic. medRxiv. Le 10 juin 2021. doi: 10.1101/2021.06.08.21258572.

Skowronski DM, Setayeshgar S, Zou M, Prystajecky N, Tyson JR, Galanis E, Naus M, Patrick DM, Sbihi H, El Adam S, Henry B, Hoang LMN, Sadarangani M, Jassem AN, Krajden M. Single-dose mRNA vaccine effectiveness against SARS-CoV-2, including P. 1 and B. 1.1. 7 variants: a test-negative design in adults 70 years and older in British Columbia, Canada. medRxiv. Le 9 juin 2021. doi: 10.1101/2021.06.07.21258332.

Bourguignon A, Arnold DM, Warkentin TE, Smith JW, Pannu T, Shrum JM, Al Maqrashi ZAA, Shroff A, Lessard M-C, Blais N, Kelton JG, Nazy I. Adjunct immune globulin for vaccine-induced thrombotic thrombocytopenia. N Engl J Med. Le 9 juin 2021. doi: 10.1056/NEJMoa2107051.

Vinh DC, Abel L, Bastard P, Cheng MP, Condino-Neto A, Gregersen PK, Haerynck F, Cicalese MP, Hagin D, Soler-Palacín P, Planas AM, Pujol A, Notarangelo LD, Zhang Q, Su HC, Casanova JL, Meyts I; COVID Human Genetic Effort. Harnessing type I IFN immunity against SARS-CoV-2 with early administration of IFN-β. J Clin Immunol. Le 8 juin 2021:1–18. doi: 10.1007/s10875-021-01068-6.

Verma AA, Hora T, Jung HY, Fralick M, Malecki SL, Lapointe-Shaw L, Weinerman A, Tang T, Kwan JL, Liu JJ, Rawal S, Chan TCY, Cheung AM, Rosella LC, Ghassemi M, Herridge M, Mamdani M, Razak F. Caractéristiques et issues des hospitalisations pour les cas de COVID-19 et d’influenza dans la région de Toronto. CMAJ. Le 7 juin 2021;193(23):E859-E869. doi: 10.1503/cmaj.202795-f.

Bullard J, Funk D, Dust K, Garnett L, Tran K, Bello A, Strong JE, Lee SJ, Waruk J, Hedley A, Alexander D, Caeseele PV, Loeppky C, Poliquin G. Comparison de l’infectivité du coronavirus du syndrome respiratoire aigu sévère 2 chez les enfants et les adultes. CMAJ. Le 7 juin 2021;193(23):E870-E877. doi: 10.1503/cmaj.210263-f.

Liu M, Arora RK, Krajden M. Tests de détection rapides d’antigènes pour le SRAS-CoV-2. CMAJ. Le 7 juin 2021;193(23):E886-E887. doi: 10.1503/cmaj.202827-f.

Reyes Domingo F, Waddell LA, Cheung AM, Cooper CL, Belcourt VJ, Zuckermann AME, Corrin T, Ahmad R, Boland L, Laprise C, Idzerda L, Khan A, Jaramillo Garcia A. Prevalence of long-term effects in individuals diagnosed with COVID-19: a living systematic review. Le 6 juin 2021. doi:10.1101/2021.06.03.21258317.

Tauzin A, Nayrac M, Benlarbi M, Gong SY, Gasser R, Beaudoin-Bussières G, Brassard N, Laumaea A, Vézina D, Prévost J, Anand SP, Bourassa C, Gendron-Lepage G, Medjahed H, Goyette G, Niessl J, Tastet O, Gokool L, Morrisseau C, Arlotto P, Stamatatos L, McGuire AT, Larochelle C, Uchil P, Lu M, Mothes W, De Serres G, Moreira S, Roger M, Richard J, Martel-Laferrière V, Duerr R, Tremblay C, Kaufmann DE, Finzi A. A single dose of the SARS-CoV-2 vaccine BNT162b2 elicits Fc-mediated antibody effector functions and T-cell responses. Cell Host and Microbe. Le 4 juin 2021. doi: 10.1016/j.chom.2021.06.001.

Betti M, Bragazzi N, Heffernan J, Kong J, Raad A. Could a new COVID-19 mutant strain undermine vaccination efforts? A mathematical modelling approach for estimating the spread of B.1.1.7 using Ontario, Canada, as a case study. Vaccines. Le 3 juin 2021; 9(6):592. doi: 10.3390/vaccines9060592.

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