Optimization of immunologic testing studies

A new testing strategy for the prompt detection of SARS-CoV-2 variants of concern

As the pandemic continues to evolve, it has become increasingly important to systematically adapt testing capacities to detect all variants of concern. In a recently published article, CITF-funded researcher Dr. Marc Romney and his team at the University of British Columbia proposed a new testing strategy that can rapidly detect circulating variants, and which [...]

SARS-CoV-2 seroprevalence survey estimates are affected by anti-nucleocapsid antibody decline

Researchers from Public Health Ontario and the University of Toronto found that there was a drop in the number of samples with detectable antibodies over time using the Abbott Architect SARS-CoV-2 IgG assay, but not when using the Ortho-Clinical Diagnostics VITROS Anti-SARS-CoV-2 IgG test. The study provides evidence that there exists potentially significant variability in assays, which may give the impression of waning protection against COVID infection.

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