Immune science

Antibody responses to circulating strains provide the greatest protection against SARS-CoV-2 infection

A CITF-supported study, published in Vaccines, suggested that higher antibody levels do not guarantee protection against COVID-19. Levels of antibodies to the original strain are not a reliable indicator to determine the need for or timing of booster dosing. Having received a bivalent vaccine (combining the original and Omicron strains) was associated with lack of a breakthrough infection during the Omicron BA.4/5 waves of the pandemic.

2024-01-15T12:15:52-05:00January 12, 2024|Immune science|

Recipients of solid organ transplant recipients can mount significant T-cell responses to the BA.4/5 and XBB.1.5 Omicron variants following mRNA vaccination against ancestral SARS-CoV-2

A CITF-funded study, published in Transplantation, provided insights into the kinetics of variant-specific T-cell responses in recipients of solid organ transplants, with the aim of informing clinical and public health guidelines for immunocompromised populations.

2023-12-18T10:16:05-05:00December 15, 2023|Immune science|
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