Extracellular vesicles promote the recovery of heart function
A CITF-funded study, published in preprint and not yet peer-reviewed, provided valuable insights into the mechanisms of myocardial inflammation and its effects on heart function using a heart-on-a-chip model.
Two doses of Moderna vaccine effective against SARS-CoV-2 infection and hospitalization in children aged 6 months to 5 years
A CITF-funded study, published in preprint and not yet peer-reviewed, found that a 2nd dose of the Moderna vaccine was associated with reduced symptomatic SARS-CoV-2 infection (vaccine effectiveness [VE]=90%), as well as reduced COVID-19-related hospitalization (VE=82%) in children aged 6 months to 5 years.
Educating adults about COVID-19 vaccines is essential to promote vaccine confidence
A CITF-funded review, published in Campbell Systematic Reviews, found that among various strategies for promoting vaccine confidence, educational interventions were introduced to support individuals in their vaccine decisions by building COVID-19 vaccine knowledge and confidence. Group-based and formal presentations were the most frequently used.
Vaccination helps reduce workplace absenteeism among Canadian healthcare workers
A CITF-funded study, published in the Journal of Occupation and Environmental Medicine, found that Canadian healthcare workers who had a positive SARS-CoV-2 test and were vaccinated against COVID-19 were less absent from work.
Fourth dose of the COVID-19 vaccine is highly immunogenic and safe in people who have received an allogeneic hematopoietic stem cell transplant
A CITF-funded study, published in Transplantation and Cellular Therapy, found that a fourth dose of the COVID-19 vaccine is highly immunogenic (induces a good immune response) and safe in people who have a received an allogeneic Hematopoietic Stem Cell Transplant (HSCT).
CITF-funded findings on seroprevalence and effects of COVID-19 on children and adolescents
Ongoing monitoring of the serological status of children is important, particularly in the context of new variants of concern, low vaccine coverage, and low uptake of testing. Here, members of the CITF Secretariat summarize results from the four presentations given during the breakout session, “Seroprevalence and effects of COVID-19 on children and adolescents,” at the CITF Scientific Meeting in Vancouver, March 8-10, 2023.
CITF-funded findings on accelerated research in long-term care settings
Studying the immune responses of older Canadians to infections and to vaccines has helped to inform the appropriate timing for booster vaccines in this vulnerable population, especially those living in long-term care (LTC) homes.
Respiratory syncytial virus antibody functions diminished during peak of COVID-19 pandemic, causing more severe RSV infections
A CITF-funded study, published in preprint and not-yet peer-reviewed, found that the almost complete absence of RSV circulation during the peak of COVID-19 pandemic mitigation measures led to waning antibody-mediated and cellular responses that protect against severe respiratory syncytial virus (RSV) infection.
Predictors of Post COVID-19 Condition
A CITF-funded study, published in preprint and not yet peer-reviewed, found positive associations between Post COVID-19 Condition (PCC), also known as Long COVID, and anti-spike (S), and anti-receptor binding domain (RBD) IgG titres, which were not statistically significant.