Publications from our Experts

Publications from our Experts2022-01-11T15:39:59-05:00

Canada’s monitoring of COVID-19 vaccine safety

Vaccine safety is evaluated by tracking adverse events following immunization to determine whether such events are linked to the vaccine. Drs. Karina Top, Julie Bettinger, and Jeffrey Kwong describe their critical efforts for monitoring COVID-19 vaccine safety in Canada, which are all supported by the CITF and Vaccine Surveillance Reference Group. The original article can be accessed on the Canadian Vaccination Evidence Resource and [...]

September 28, 2021|Publications from our experts|

COVID-19 serology tests are not all the same, but they are all useful!

An international team of experts conducted a multi-laboratory evaluation of 21 commercial high-throughput assays used in laboratories to determine whether someone has antibodies to SARS CoV-2 proteins, using 1,000 blood-donor samples. CITF Testing Working Party Lead Dr. Mel Krajden and Testing Working Party member Dr. Steven Kleinman were among the experts involved. Some assays recognized all possible antibodies (total Ig assays), while others recognized [...]

September 28, 2021|Publications from our experts|

Pregnancy and the Risk of Severe COVID-19 Infection: Methodologic Challenges and Research Recommendations

This commentary From Dr. David Savitz and CITF-funded researcher Dr. Deshayne Fell outlines specific methods that should be implemented in research to more effectively assess the risk of severe COVID-19 among pregnant individuals. The article touches upon methodological challenges including increased surveillance, enhanced clinical responses to illness, and confounding. It also gives an overview of the current evidence on COVID-19 and pregnancy while offering [...]

September 28, 2021|Publications from our experts|

Mental health concerns among sexual health service clients in the early days of the COVID-19 pandemic

In a recent Short Communication in Preventive Medicine, CITF Leadership Group member Dr. Gina Ogilvie, CITF-funded researcher Dr. Daniel Grace and colleagues explore the mental health of sexual health service clients, an example of a marginalized community. They found that 55% of respondents self-rated their mental health as being poor at the beginning of the COVID-19 pandemic. Mental health concerns are common among those [...]

September 21, 2021|Publications from our experts|

Are people with autoimmune disease more likely to have COVID-19?

A study by researchers at the University of Toronto, in collaboration with CITF-funded researcher Dr. Sasha Bernatsky from the Research Institute of the McGill University Health Centre, observed that people with autoimmune diseases had the same proportion of SARS-CoV-2 positive tests and a similar disease incidence compared to the general population in 2020. However, testing for COVID-19 is higher than in the general population. [...]

September 21, 2021|Publications from our experts|

Increasing evidence regarding antibodies in saliva following COVID-19 infection or vaccination

Individuals who have recovered from COVID-19 or who have received SARS-CoV-2 vaccines (mRNA or adenovirus-based) have been shown to have virus-neutralizing activity in their saliva. These results appeared in a recent pre-print, therefore not yet peer reviewed, directed by scientists from Stanford University School of Medicine, with contributions from CITF-funded researchers Drs. Jennifer Gommerman, Allison McGeer, Anne-Claude Gingras, and Sharon Straus. Previous infection or [...]

September 14, 2021|Publications from our experts|

Mental illness and substance use also linked to increased risk of hospitalization

In a preprint that has not been peer-reviewed, CITF Leadership Group member Dr. Mel Krajden and colleagues sought to identify factors associated with COVID-19 hospitalization by looking at all individuals with lab-confirmed SARS-CoV-2 in British Columbia as of January 15, 2021. Of all factors identified, it is one of the first reports linking mental illness and substance use with increased risk of COVID-19-related hospitalization. [...]

September 7, 2021|Publications from our experts|

The need to improve vaccine messaging and outreach: COVID-19 vaccine intention among women and gender-diverse individuals living with HIV in British Columbia

In their recent pre-print, not yet peer-reviewed, CITF Leadership Group member Dr. Gina Ogilvie, VSRG Working Group member Dr. Manish Sadarangani and colleagues in British Columbia explored COVID-19 vaccination intention among women and gender diverse individuals living with HIV. The authors report that the intention to get a vaccine in these groups was significantly lower than among their peers, despite the safety and effectiveness [...]

August 31, 2021|Publications from our experts|

Newly discovered rogue antibodies: why some older adults are at higher risk of severe COVID-19 illness

A collaborative effort of over 150 scientists from over 20 countries, including CITF-funded researcher Dr. Donald Vinh from McGill University Health Centre and the Research Institute of the McGill University Health Centre, has led to the identification of a surprisingly high prevalence of a type of antibody that has been linked to fatal outcomes of COVID-19. These autoantibodies – antibodies that mistakenly target a [...]

August 31, 2021|Publications from our experts|
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