Leveraging the use of type 1 interferons as therapeutics against severe COVID-19
While many effective vaccines have been developed to mitigate the impact of the COVID-19 pandemic, there remains a critical need for novel ways of treating patients hospitalized with moderate, severe or critical COVID-19.
Pregnancy and neonatal outcomes in the COVID-19 pandemic era
As the pandemic progresses, we are learning more about COVID-19 and its effects on pregnancy.
Characteristics of children admitted to hospital with acute SARS-CoV-2 infection in Canada in 2020
In a recent Canadian Medical Association Journal (CMAJ) publication, CITF-funded researchers Drs. Karina Top (Dalhousie University), Manish Sadarangani (University of British Columbia), Jesse Papenburg (McGill University), and led by Drs. Fatima Kakkar and Shaun Morris, described 264 children who were admitted to hospital in Canada with confirmed SARS-CoV-2 infection in 2020.
Vaccine effectiveness of SARS-CoV-2 vaccines in British Columbia
Canada and other countries globally have authorized different SARS-CoV-2 vaccines, mostly based on findings from clinical trials which have demonstrated a high degree of efficacy against disease.
Higher prevalence of SARS-CoV-2 infection among people experiencing homelessness in Toronto during the first wave of the COVID-19 pandemic
A recent pre-print (therefore, not yet peer-reviewed) led by CITF-funded researcher Dr. Stephen Hwang from the University of Toronto and Unity Health, explored the prevalence of SARS-CoV-2 among people experiencing homelessness in Toronto during the first wave of the pandemic.
Canada’s monitoring of COVID-19 vaccine safety
Vaccine safety is evaluated by tracking adverse events following immunization to determine whether such events are linked to the vaccine.
COVID-19 serology tests are not all the same, but they are all useful!
An international team of experts conducted a multi-laboratory evaluation of 21 commercial high-throughput assays used in laboratories to determine whether someone has antibodies to SARS CoV-2 proteins, using 1,000 blood-donor samples.
Pregnancy and the Risk of Severe COVID-19 Infection: Methodologic Challenges and Research Recommendations
This commentary From Dr. David Savitz and CITF-funded researcher Dr. Deshayne Fell outlines specific methods that should be implemented in research to more effectively assess the risk of severe COVID-19 among pregnant individuals.
Mental health concerns among sexual health service clients in the early days of the COVID-19 pandemic
In a recent Short Communication in Preventive Medicine, CITF Leadership Group member Dr. Gina Ogilvie, CITF-funded researcher Dr. Daniel Grace and colleagues explore the mental health of sexual health service clients, an example of a marginalized community. T